NCT00492934Unknown不适用
Natural Cycle Versus Stimulation With Human Menopausal Gonadotropin in Cycles With Cryopreserved Embryos
University Hospital, Gasthuisberg1 个研究点 分布在 1 个国家目标入组 300 人开始时间: 2004年1月最近更新:
适应症
干预措施
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- implantation rate per embryo
研究概览
简要总结
The study investigates if, among women with a regular cycle (between 25 and 45 days), the endometrium is better prepared for the transfer of an embryo that was cryopreserved and if the subsequent embryo implantation rate is higher when the cycle is started with daily, small-dose hormonal injections than in cycles without these daily injections.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 21 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Signed informed consent.
- •Women with a regular cycle (between 21 and 35 days).
- •Embryos with 50% intact blastomeres after thawing.
- •Embryo and endometrium are synchronized.
排除标准
- •Embryo storage time not longer than 5 years.
研究组 & 干预措施
1
Active Comparator
Daily injections with a small dose of gonadotrophins from day 2 of the cycle
干预措施: human menopausal gonadotrophins (Drug)
结局指标
主要结局
implantation rate per embryo
时间窗: 15 days after the embryo transfer
次要结局
- thickness of the endometrium(0-2 days before the human chorionic gonadotropin (hCG) injection)
研究者
Thomas D'Hooghe
Professor, Medical Doctor
University Hospital, Gasthuisberg
研究点 (1)
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