Erector spinae plane block (block given in the back) for pain relief following kidney stone surgery

Not yet recruiting

• Conditions: Calculus of kidney, (2) ICD-10 Condition: O||Medical and Surgical,

• Registration Number: CTRI/2022/08/045033
• Lead Sponsor: M S Ramaiah Medical College

Brief Summary

Percutaneous nephrolithotomy (PCNL) is currently thefrequently employed surgical procedure for the removal of large complex renaland proximal ureteric calculi. Being minimally invasive it hasless morbidity, and allows early recovery and ambulation after surgery. Postoperativepain following PCNL has both visceral and somatic components. Visceralcomponent arises from the kidney, renal capsule and ureter, while the somaticcomponent from the skin incision and the nephrostomy tract. The nephrostomy tube that is inserted at the end of the procedure can elicitinflammatory reaction leading to pain and discomfort.

Although PCNL is a minimally invasive procedure,postoperative pain can be severe and inadequate postoperative analgesia is abarrier to early recovery after surgery. Systemic analgesics like opioids,non-steroidal anti-inflammatory drugs (NSAIDs) and paracetamol form themainstay for providing pain relief. However, opioids are associated with sideeffects like nausea, vomiting, pruritus, constipation, and respiratorydepression, while NSAIDs may be relatively contraindicated in these patientswho may have compromised renal function.

Regional anaesthetic techniques like intercostalnerve block, paravertebral block, epidural analgesia, peritubal infiltrationand subcutaneous infiltration have been employed for providing postoperativeanalgesia following PCNL.Erector spinae plane [ESP] block is arecently described interfascial  planeblock for providing postoperative analgesia following thoracic and abdominalsurgeries.Its use for providing pain relief following PCNL isrecently been described in literature,  However , there is paucityof literature providing its efficacy following PCNL surgery. Hence, the presentstudy is designed to evaluate its role in providing postoperative analgesiafollowing PCNL.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-01-09
• Last Update Posted: 2022-08-26

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 88

Inclusion Criteria

American Society of Anaesthesiology physical status 1 and 2 Unilateral Percutaneous Nephrolithotomy Surgery.

Exclusion Criteria

BMI ≥ 35kg/m2 Bilateral PCNL Chronic analgesic use Allergy to local anaesthetics Contraindications to ESP block Cognitive dysfunction Pregnancy Spine deformity Relook Percutaneous Nephrolithotomy Surgery.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Total analgesic requirement in the first 24 hours after surgery	Total analgesic dose consumed will be assessed at the end of 24 hours after surgery.

Secondary Outcome Measures

Name	Time	Method
Postoperative pain	Pain assessed at intervals of 30 minutes, 1 hour, 2 hours, 4 hours, 6 hours, 12 hours and 24 hours after surgery
Time to first demand of rescue analgesia

Trial Locations

Locations (1)

M S Ramaiah Medical College Hospital; 🇮🇳 Bangalore, KARNATAKA, India

M S Ramaiah Medical College Hospital

🇮🇳Bangalore, KARNATAKA, India

Dr Tejesh C A

Principal investigator

9886481848

drtejeshca@yahoo.com