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临床试验/NCT04998435
NCT04998435已完成不适用

Ultrasound-Guided Paravertebral Block Versus Erector Spinae Plain Block For Perioperative Analgesia In Adults Undergoing Percutaneous Nephrolithotomy: A Randomized Clinical Trial

Nazmy Edward Seif1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2021年8月11日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
50
试验地点
1
主要终点
Morphine consumption.

研究概览

简要总结

Nowadays, Percutaneous Nephrolithotomy (PCNL) has been the surgical procedure of choice for renal stones larger than 2cm or staghorn stones. Yet, the associated postoperative pain is a major drawback. The regional anesthetic management of pain in PCNL operation has been of great concern. The introduction of ultrasound guided erector spinae plane block and paravertebral plane block has been under great focus regarding the efficacy of postoperative pain management. Paravertebral plane block (PVB) is a regional nerve block technique that depends on local anesthetic injection adjacent to the vertebra to block spinal nerve roots in a dermatomal distribution. Erector spinae plane block (ESPB) is a newer regional anesthesia technique that depends on injecting local anesthetic (LA) in a plane between the transverse process and erector spinae muscle. The LA diffuses into the paravertebral space and spreads on both rami (dorsal and ventral) of spinal nerves through spaces between adjoining vertebrae.

The aim of this study is to compare the effect of ultrasound guided Paravertebral blockade versus Erector spinae blockade on postoperative opioid use as well as postoperative pain control in patients undergoing unilateral PCNL.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Supportive Care
盲法
Double (Participant, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • ASA I - II.
  • Patients undergoing unilateral percutaneous nephrolithotomy (PCNL) surgery under general anesthesia.

排除标准

  • Patient refusal.
  • Uncooperative patients.
  • Allergy to local anesthetics.
  • Infection or anatomical abnormality at injection site.
  • Coagulopathy.
  • Bilateral PCNL.
  • Spinal anesthesia or any other regional anesthesia.
  • Block failure: the block will be considered a failed block if the patient requires more than two doses of rescue analgesia in the first hour postoperatively.

结局指标

主要结局

Morphine consumption.

时间窗: 24 hours

Total dose of Morphine (measured in mg) given intra-venously to the patient post-operatively.

次要结局

未报告次要终点

研究者

发起方
Nazmy Edward Seif
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Nazmy Edward Seif

Clinical Professor

Cairo University

研究点 (1)

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