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Clinical Trials/NCT04800302
NCT04800302
Completed
Not Applicable

Ultrasound-guided Continuous Quadratus Lumborum Block III for Postoperative Analgesia in Percutaneous Nephrolithotomy

Nazmy Edward Seif1 site in 1 country45 target enrollmentJune 10, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Analgesia
Sponsor
Nazmy Edward Seif
Enrollment
45
Locations
1
Primary Endpoint
Morphine consumption.
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

Percutaneous nephrolithotomy (PCNL) is considered to be the first choice and a more conservative procedure than open stone surgery. Not only postoperative pain related to dilatation of the renal capsule and parenchymal tract, but also patient's discomfort & nephrostomy tube-related stress are reported to delay recovery time and increase the complication rates. This study is designed to provide postoperative analgesia by using ultrasound-guided continuous Quadratus Lumborum Block (QLB) III in patients undergoing PCNL and to assess pain scores & side effects with less opioids consumption.

Registry
clinicaltrials.gov
Start Date
June 10, 2021
End Date
June 28, 2022
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Nazmy Edward Seif
Responsible Party
Sponsor Investigator
Principal Investigator

Nazmy Edward Seif

Clinical Professor

Cairo University

Eligibility Criteria

Inclusion Criteria

  • ASA I-II.
  • Scheduled for percutaneous nephrolithotomy (PCNL).

Exclusion Criteria

  • Patient refusal.
  • Coagulation disorders.
  • Skin lesions or infection at site of needle insertion.
  • Known allergy to local anesthetics or opioids.
  • Patients suffering from neurological or mental disease.
  • Procedure turned into open stone surgery.
  • Failure of identification by U/S.
  • Urinary tract malignancies.
  • Opioid consumption 48 hours before the operation.

Outcomes

Primary Outcomes

Morphine consumption.

Time Frame: 24 hours

Total dose of Morphine (measured in mg) given intra-venously to the patient post-operatively.

Study Sites (1)

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