Effectiveness of thiamine in treatment of depressio
Not Applicable
- Conditions
- Major Depressive Disorder.Depressive episode
- Registration Number
- IRCT2013070913929N1
- Lead Sponsor
- Vice chancellor for Research and Technology of Hamadan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
- Diagnosis of major depressive disorder (MDD), according to DSM-V
-Age between 18 to 50 years.
Exclusion criteria:
- Patients with other psychiatric disorders, along with major depression
-Debilitating somatic illness, along with major depression
-Suffering from Wernicke Syndrome
-History of alcohol or substances abuse in the last year
-Known gastrointestinal disease
-History of long-term dialysis
-Suffering from congestive heart failure with long-term use of diuretics
-Magnesium deficiency
-Suffering from anorexia nervosa
-Allergy and sensitivity to thiamine
-Thiamine deficiency in laboratory evaluation
-Hyperthyroidism
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Severity of symptoms of Depression. Timepoint: Baseline and 3weeks, 6weeks ,12weeks after treatment. Method of measurement: Hamilton Depression Rating Scale.
- Secondary Outcome Measures
Name Time Method