Rhinosinusites Chroniques

Not Applicable

• Conditions: Refractory; Chronic Disease; Sinusitis

• Registration Number: NCT02407275
• Lead Sponsor: Institut Hospitalo-Universitaire Méditerranée Infection

Brief Summary

To analyse and describe sinus microbiota, during hard to treat (or refractory) rhinosinusitis, using culturomic and metagenomic methods (i.e. to culture on many different medium of culture to grow hard to cultivate bacteria + to sequence and analyse all DNA contained in samples).

Samples are middle meatus swabs or pus aspiration, done during usually patient following.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-02
• Status Verified: 2015-03
• Study First Submitted: 2015-03-30
• Study First Submitted QC: 2015-03-30
• Last Update Submitted: 2015-03-30
• Study First Posted: 2015-04-02
• Last Update Posted: 2015-04-02
• Primary Completion: 2015-09

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• >18 year old
• chronic refractory rhinosinusitis
• to require middle meatus swab or other sinus sample
• absence of opposition

Exclusion Criteria

• <18 year old
• pregnant women
• breastfeeding
• under trusteeship
• under guardianship

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Sinusian microbiota description	6 months	species, number and type of isolated microbes

Trial Locations

Locations (1)

Service ORL et de Chirurgie Cervico - Faciale/ AP-HM; 🇫🇷 Marseille, France