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The study of CYP2D6 genetic polymorphisms in Thai army personnel on the Thailand- Cambodia border area

Phase 4
Completed
Conditions
Malaria
Malaria&#44
CYP 2D6 genetic polymorphisms
Registration Number
TCTR20180831005
Lead Sponsor
Phramongkutklao College of Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Male
Target Recruitment
260
Inclusion Criteria

1. Thai army male who has been performed in Thai-Cambodia border areas
2. Aged 18-60 years
3. Who had history with malaria infection from the Thai-Cambodia border area

Exclusion Criteria

Who known history of G6PD deficiency

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
the frequency of CYP 2D6 genetic polymorphism in Thai army personnel on the Thailand-Cambodia border after counselling (participants according to inclusion criteria) real-time PCR and extra-long PCR
Secondary Outcome Measures
NameTimeMethod
the correlation of CYP 2D6 genetic polymorphism and Plasmodium vivax relapse after gene analysis Chi-square test
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