The Effect of genetic polymorphism of CYP2B6 and UGT1A9 on the Pharamcokinetics and Pharmacodynamics of Propofol
Not Applicable
- Conditions
- The patients are surgical operation with propofol in the St. Marianna University Hospital
- Registration Number
- JPRN-UMIN000002009
- Lead Sponsor
- St. Marianna University School of Medicine, Department of Pharmacogenomics
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up continuing
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Not provided
Exclusion Criteria
The patients did not informed consent. The propofol administration dosage is varied. The patients are transfusion during surgical operation. The patients have infection. The patients is under the confusion, ileus, agnosis, resection of stomach, disorder of liver function, disorder of kidney function, suppress of breathing, chronic obstructive pulmonary disease, asthma, heart failure with chronic pulmonary disease, and/or seizure. The medical doctor is estimate that the patients cannot entry of study
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The recovery of consciousness time, polymorphism of CYP2B6 and UGT1A9
- Secondary Outcome Measures
Name Time Method Pharmacokinetics parameter of propofol