Magnetic resonance image analysis for quantification of knee articular cartilage verified response to etanercept(ETN) in subjects with active rheumatoid arthritis
- Conditions
- rheumatoid arthritis
- Registration Number
- JPRN-UMIN000005773
- Lead Sponsor
- 22nd Century Medical & Research Center, the University of Tokyo
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 20
Not provided
1. Patient does not meet the guideline of anti-TNF therapy in RA patients. 2. Patient is septicemic or at risk of sepsis. 3. Patient has serious infection. 4. Patient has active tuberculosis. 5. Patient has a history of hypersensitivity to ingredients of the study drugs (ETN and MTX). 6. Patient has any current or previous demyelinating diseases. 7. Patient has congestive heart failure. 8. Patient cannot be treated with MTX ( 6 mg/week) in RA patients. 9. Patient has bone marrow suppression. 10. Patient has chronic hepatic disease. 11. Patient has renal dysfunction. 12. Patient is a nursing woman. 13. Patient is pregnant or possibly pregnant. 14. Patient has pleural effusion or ascites 15. Patient has contraindications for MRI 16. Patient is otherwise ineligible to participate in this study in the investigator's opinion.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method