Osteogenesis Imperfecta and Balance

Not Applicable

Recruiting

• Conditions: Osteogenesis Imperfecta

• Registration Number: NCT06010134
• Lead Sponsor: South Valley University

Brief Summary

Osteogenesis Imperfecta (OI), also known as brittle bone disease, is a group of genetic disorders that mainly affect the bones. It results in bones that break easily. Its severity may be mild to severe. Other symptoms may include a blue tinge to the whites of the eye, short height, loose joints, hearing loss, breathing problems and problems with the teeth.

Physiotherapy is aimed to strengthen muscles and improve motility in a gentle manner, while minimizing the risk of fracture, and the use of support cushions to improve posture.

Detailed Description

This study aimed to assess the efficacy of Whole Body Vibration on balance and motor function in children with Osteogenesis Imperfecta.

Whole body vibration (WBV) therapy is targeted at musculoskeletal strengthening and has been trialed in a variety of conditions. WBV has been shown to have therapeutic advantage in various osteopenic preclinical models and populations such as postmenopausal women (improved mobility, muscle strength, postural strength, and bone density) and children with osteogenesis imperfecta (improved mobility)

Study Timeline

• Status Verified: 2023-05
• Study Start: 2023-05-01
• Study First Submitted: 2023-08-17
• Study First Submitted QC: 2023-08-17
• Last Update Submitted: 2023-08-17
• Study First Posted: 2023-08-24
• Last Update Posted: 2023-08-24
• Primary Completion: 2023-08-30
• Study Completion: 2023-09-30

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1. Their age was ranging from six to twelve years
2. Children participated in this study were from both sexes
3. All children with stable medical and psychological status.
4. They were able to follow the verbal commands or instructions during testing.

Exclusion Criteria

1. Children with visual or auditory problems.
2. Children with any cognitive problems.
3. Children without deformity

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Antro posterior Stabiity Index	at day 90	Stabiity Index
Medio lateral Stabiity Index	at day 90	Stability Index
Over All Stabiity Index	at day 90	Stability Index

Trial Locations

Locations (1)

South Valley University, Faculty of Physical Therapy; 🇪🇬 Qina, Egypt