The Effect of a Multi-component Weight Management Program on Appetite, Food Preference and Body Weight
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 96
- 试验地点
- 2
- 主要终点
- Test Meal Energy Intake
研究概览
简要总结
The aim of the current study is to demonstrate that a commercial weight management diet (i.e. low energy density) influences satiation, hunger and satiety and leads to lower energy intake during ad-libitum meals and over a full day. We further seek to demonstrate the sustainability of this effect following 12- week weight loss on the weight management program.
- We hypothesise that formulated (low energy) meals will lead to decreased hunger, greater fullness and reduced desire to eat compared to standard meals.
- We hypothesise that the commercial weight management program will lead to greater weight loss compared to control program.
- We hypothesise that formulated meals (high consumer acceptance) will improve hedonic control over eating (lower wanting for high fat food)
- We hypothesise that the commercial weight management program will improve hedonic control over eating (reduced experience food cravings)
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •BMI of 28 - 45 kg/m2
- •Reporting an interest in weight loss, not actively participating in a commercial weight loss program,
- •Not increased physical activity levels in the past 2-4 weeks
- •Able to eat most everyday foods and fruits and vegetables
- •Written informed consent to be given
排除标准
- •Significant health problems that could cause confounding effects between intervention and control.
- •Taking any medication or supplements known to affect appetite or weight within the past month and/or during the study
- •Pregnant, planning to become pregnant or breastfeeding
- •History of anaphylaxis to food
- •Known food allergies or food intolerance
- •Smokers and those who have recently ceased smoking
- •Participants receiving systemic or local treatment likely to interfere with evaluation of the study parameters
- •Those who have previously taken part in a commercial weight loss program in the last 6 months? .
- •Participants who work in appetite or feeding related areas
- •Participants unable to consume foods used in the study
- •Participants who have had bariatric surgery
- •Participants with a history of eating disorder
- •Presence of untreated hypothyroidism
- •Inability to fully comply with intervention or study procedures
- •Insufficient English language skills to complete study questionnaires
结局指标
主要结局
Test Meal Energy Intake
时间窗: Week 0 and week 12
Measured reductions in ad-libitum energy intake following consumption of formulated test meal in comparison to control.
Food preference
时间窗: Week 0 and week 14
Measured changes in food preference and liking and wanting profiles for food (HF\<LF) following consumption of formulated test meal in comparison to equi-energetic control
24h Energy Intake
时间窗: Week 0 and week 12
Measured reduction in total within-day energy intake following consumption of formulated meals in comparison to control
Appetite sensations
时间窗: Week 0 and week 14
Measured reduction in hunger and increase in satiety quotient following consumption of formulated test meal in comparison to equi-energetic control
次要结局
- Body Weight(Weekly from week 0 to week 12)
研究者
Dr Graham Finlayson
Principal Investigator
University of Leeds