The effect of intravenous fluid preload on diuresis during spinal anesthesia-induced detrusor blockade

• Conditions: Diuresis during spinal anesthesia; MedDRA version: 9.1Level: LLTClassification code 10041538Term: Spinal anesthesia; MedDRA version: 9.1Level: LLTClassification code 10013523Term: Diuresis

• Registration Number: EUCTR2007-000702-71-NL
• Lead Sponsor: Alysis Zorggroep

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2007-07-12
• Last Update Posted: 19 March 2012

Recruitment & Eligibility

• Status: Authorised-recruitment may be ongoing or finished
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

patients planned for short, minor surgery of lower extremity under spinal anesthesia.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

any urologic, neurologic, cardiac, vascular disease.

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Main Objective: Determine effects of intravenous fluid preload (given just before spinal anesthesia) on volume of diuresis during spinal anesthesia induced detrusor blockade;Secondary Objective: Determine effects of intravenous fluid preload in preventing hypotension;Primary end point(s): 1) mean volume of diuresis during spinal anesthesia<br>2) number of subjects with diuresis volume over 500 ml