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临床试验/NCT02481362
NCT02481362已完成不适用

Food Choices in Healthy Weight Women

The University of Tennessee, Knoxville2 个研究点 分布在 1 个国家目标入组 28 人开始时间: 2015年6月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
28
试验地点
2
主要终点
Grams of consumption of cake

研究概览

简要总结

This study will examine differences in habituation to foods high in sugar and fat content versus those that are not, in normal weight women.

详细描述

Participants will complete two experimental sessions, in which habituation to chocolate cake and dried apricots will be measured, with each session measuring habituation rate to one food. Upon arrival to the session, participants will write down what they have consumed and the minutes of physical activity they have engaged in during the previous 24 hours. Participants will rate their feelings of hunger and fullness using a 100mm VAS. They will also rank their liking of the food being used in the session using a 100mm VAS. Participants will be given a peanut butter flavored granola bar, containing 190 kcal, and be instructed to consume all of the bar.

Next, participants will complete a computer generated task to measure habituation to a food (chocolate cake or apricots). The computer task will be programmed at a variable interval of 120 ± 42 seconds (VI-120) reinforcement schedule, so that participants will be rewarded one point for the first response made after approximately 120s have passed. The computer task consists of two squares, one that flashes red every time a mouse button is pressed and another square that flashes green when a point is earned. The habituation phase will be 24 minutes, divided into 12, 2-minute trials, during which participants can earn points towards access to 75 kcal portions of the food that is being measured. Participants will receive the food immediately after each point is earned to consume and can continue to play the computer task while eating. Participants will be instructed that when they no longer want to earn access to the food they can go to another table and engage in the activities provided (i.e., reading magazines). After the computer task, participants will rate their feeling of hunger, fullness, and liking of the food. During the computer task the number of consecutive two-minute time blocks before responding ceases, as well as the overall pattern of responding, will be measured.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Basic Science
盲法
Single (Participant)

入排标准

年龄范围
18 Years 至 35 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • body mass index (BMI) 18.5 to 24.9 kg/m2
  • nonsmokers
  • not allergic to the foods used in the investigation
  • must like the foods in the investigation (scoring > 50 mm on a visual analogue scale [VAS])
  • be willing to consume the foods
  • not have dietary restrictions
  • not be a restrained eater (scoring > 12 on the Three Factor Eating Scale)
  • not be on medications that influence appetite
  • not planning to change their diet or physical activity during the time frame of their study participation
  • not dieting or trying to lose weight.

排除标准

  • BMI outside of the range 18.5-24.9
  • food allergies
  • does not like the foods used in the study
  • has dietary restrictions
  • is a restrained eater
  • on medications that may influence appetite
  • planning on changing diet or physical activity during time frame of the study
  • trying to lose weight

研究组 & 干预措施

Order 1

Active Comparator

Order for sessions: Cake, apricots

干预措施: APRICOTS (Other)

Order 2

Active Comparator

Order for sessions: apricots, Cake

干预措施: CAKE (Other)

Order 2

Active Comparator

Order for sessions: apricots, Cake

干预措施: APRICOTS (Other)

Order 1

Active Comparator

Order for sessions: Cake, apricots

干预措施: CAKE (Other)

结局指标

主要结局

Grams of consumption of cake

时间窗: 60 minutes

Amount of cake consumed will be measured using the following formula: amount of cake before consumption (first weight) - amount of cake following consumption (second weight).

Grams of consumption of apricots

时间窗: 60 minutes

Amount of apricots consumed will be measured using the following formula: amount of apricots before consumption (first weight) - amount of apricots following consumption (second weight).

次要结局

未报告次要终点

研究者

发起方
The University of Tennessee, Knoxville
申办方类型
Other
责任方
Principal Investigator
主要研究者

Hollie Raynor

Professor

The University of Tennessee, Knoxville

研究点 (2)

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