Effect of platelet counts and activator in platelet rich plasma (PRP) for the treatment of androgenetic alopecia.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 82
- 试验地点
- 1
- 主要终点
- To evaluate hair counts hair density hair thickness
研究概览
简要总结
Androgenetic alopecia is a common chronic hair loss disorder, characterized by stepwise miniaturization of hair follicle, resulting from alteration in the hair cycle dynamics, leading to vellus transformation of terminal hair follicle. Diagnosis will be stablished by history, examination, dermoscopic features and grade according to Hamilton Norwood scale. base line platelet count have been done. PRP will be prepared by collecting 18cc of fresh blood in sodium citrate containing vacutainer. The tube will rotated in a cectrifugation machine at 2200 revolutions per minutes. plasma will be collected in another test tube and underwent a second centrifugation at 3500 rpm for 10 minutes.the lower one third contain PRP that will injected in scal;p with the help of insulin syringe.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Double Blind Double Dummy
入排标准
- 年龄范围
- 20.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- Male
入选标准
- •Patient of androgenetic alopecia having Halminton norwood scale 2-5.
排除标准
- •All the patient using topical minoxidil finasteride and systemic finasteride for at least 3 month Patient not giving informed consent or unable to understand the protocol and uncooperative patients any inflammation erythema or scaling over scalp Patient who have history of malignancies platelet disorders anemia or bleeding disorder bone marrow aplasia uncontrolled diabetes sepsis and cancer Patient who are known to be HIV hepatitis B or C positive or immunocompromised Patients who have active skin disease or skin infection at the intended treatment area Patients with a propensity for keloids Patients on antiplatelet drug like aspirin or non steroidal anti inflammatory drugs Patients taking drugs known to cause alopecia like anticoagulants beta blocker ACE inhibitors OCP valproic acid lithium etc.
结局指标
主要结局
To evaluate hair counts hair density hair thickness
时间窗: six months
次要结局
- Subjective assessment using questionaire(six months)