Influence of Synacthen Infusion on the Results of Adrenal Venous Sampling in Patient With Primary Aldosteronism

Phase 4

• Conditions: Primary Aldosteronism
• Interventions: Drug: Synacthen infusion during adrenal venous sampling

• Registration Number: NCT02127840
• Lead Sponsor: Charles University, Czech Republic

Brief Summary

The project is aimed to determine the value of synacthen infusion on the results of adrenal venous sampling in patients examined for primary aldosteronism

Detailed Description

We aim to compare the results of adrenal venous sampling performed without and during synacthen infusion.

Study Timeline

• Study Start: 2011-03
• Status Verified: 2014-04
• Study First Submitted: 2014-04-25
• Study First Submitted QC: 2014-04-28
• Last Update Submitted: 2014-04-28
• Study First Posted: 2014-05-01
• Last Update Posted: 2014-05-01
• Primary Completion: 2014-12
• Study Completion: 2014-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Confirmed primary aldosteronism

Exclusion Criteria

Inability to undergo unilateral adrenalectomy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Synacthen	Synacthen infusion during adrenal venous sampling	Synacthen infusion during adrenal venous sampling

Primary Outcome Measures

Name	Time	Method
To verify whether Synacthen infusion may influence the results of adrenal venous sampling in patients with primary aldosteronism	End of clinical examination procedure, i.e. within 4 week after adrenal venous sampling is performed.

Trial Locations

Locations (1)

University Hospital Hradec Kralove; 🇨🇿 Hradec Kralove, Czech Republic