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Tetracosactide is a diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency.
Tetracosactide is a diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency.
Cosyntropin combines with a specific receptor in the adrenal cell plasma membrane and, in patients with normal adrenocortical function, stimulates the initial reaction involved in the synthesis of adrenal steroids (including cortisol, cortisone, weak androgenic substances, and a limited quantity of aldosterone) from cholesterol by increasing the quantity of the substrate within the mitochondria. Cosyntropin does not significantly increase plasma cortisol concentration in patients with primary or secondary adrenocortical insufficiency.
For use as a diagnostic agent in the screening of patients presumed to have adrenocortical insufficiency.
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