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A Study Assessing the Health-Related Quality of Life (HRQoL) in Participants With Relapsed and/or Refractory Multiple Myeloma (RRMM) With Triple Class Exposure

Completed
Conditions
Multiple Myeloma
Registration Number
NCT05217082
Lead Sponsor
Bristol-Myers Squibb
Brief Summary

The purpose of this observational study is to assess HRQoL in relapsed and/or refractory multiple myeloma (RRMM) participants who have previously received a proteasome inhibitor, an immunomodulatory agent, and an anti-CD38 antibody.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
35
Inclusion Criteria
  • Must have sufficient command of the Japanese language to understand the study instructions and requirements

  • Must be a resident of Japan

  • Must have received prior treatment with:

    1. a proteasome inhibitor,
    2. an immunomodulatory agent, and
    3. an anti-CD38 antibody Subjects must be either 2-4 months, 5-7 months, or 8-11 months post triple class therapy exposure at time of consent
  • Subject must be diagnosed with multiple myeloma

Exclusion Criteria
  • Participants enrolled in a clinical trial that includes at least one novel/ experimental agent at the point of questionnaire completion

Other protocol-defined inclusion/exclusion criteria apply.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Health-Related Quality of Life (HRQoL) in specific domains: Fatigue, as measured by EORTC QLQ-C30Up to 1 year

EORTC QLQ-C30 defined as European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-C30

HRQoL in specific domains: Pain, as measured by the EORTC QLQ-C30Up to 1 year
HRQoL in specific domains: Cognitive Functioning, as measured by the EORTC QLQ-C30Up to 1 year
HRQoL in specific domains: Global health, as measured by the EORTC QLQ-C30Up to 1 year
HRQoL in specific domains: Disease Symptoms as measured by the EORTC QLQ-MY20Up to 1 year

EORTC QLQ-MY20 defined as European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-MY20

HRQoL in specific domains: Physical Functioning as measured by the EORTC QLQ-C30Up to 1 year
HRQoL in specific domains: Side effects as measured by the EORTC QLQ-MY20Up to 1 year
Secondary Outcome Measures
NameTimeMethod
HRQoL in specific domains: Symptoms Scale as measured by the EORTC QLQ-C30Up to 1 year
HRQoL in specific domains: Body Image as measured by the EORTC QLQ-MY20Up to 1 year
HRQoL in specific domains: Functional Scale as measured by the EORTC QLQ-C30Up to 1 year
HRQoL in specific domains: Generic HRQoL as measured by the EQ-5D-5LUp to 1 year
HRQoL in specific domains: Global Health Status as measured by the EORTC QLQ-C30Up to 1 year
HRQoL in specific domains: Future Perspective as measured by the EORTC QLQ-MY20Up to 1 year

Trial Locations

Locations (1)

Local Institution - 0001

🇺🇸

Morrisville, North Carolina, United States

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