Symptomatic and Incidental RCC Detection

Not yet recruiting

• Conditions: Patients Treated for Renal Lesions at the Urology Department of University Hospital Královské Vinohrady

• Registration Number: NCT07004426
• Lead Sponsor: Charles University, Czech Republic

Brief Summary

Evaluation of the frequency of symptomatic and incidental detection of renal carcinoma at different stages depending on the imaging modality used

Detailed Description

In the Czech Republic, there is no screening program for renal cell carcinoma. Existing evidence suggests that incidental detection of this cancer tends to occur in its early stages, which are more manageable due to effective treatment options, ultimately reducing renal cancer mortality. This highlights the potential value of evaluating current imaging modalities and determining their role in secondary prevention. This cross-sectional study, based on hospital data, aims to contribute to a better under-standing of this issue and to assess the effectiveness of imaging techniques in the early detection of renal cell carcinoma. Furthermore, data analysis may reveal the influence of risk factors on the detection of tumors at various stages.

Study Timeline

• Status Verified: 2025-05
• Study First Submitted: 2025-05-27
• Study First Submitted QC: 2025-05-27
• Last Update Submitted: 2025-05-27
• Study Start: 2025-06-01
• Study First Posted: 2025-06-04
• Last Update Posted: 2025-06-04
• Primary Completion: 2025-07-01
• Study Completion: 2025-07-15

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

• patients over 18 years of age undergoing surgical treatment for renal lesions

Exclusion Criteria

• patients undergoing surgery for non-renal and urotelial carcinoma, including unknown
• patients with recurrent renal lesions

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Detection-specific renal cell carcinoma (RCC) proportions	From 2011 to 2020	Detection-specific renal cell carcinoma (RCC) proportions, defined as the proportion of each detection type relative to all RCC cases. Results will be stratified by stage, histological type, and imaging modality.

Secondary Outcome Measures

Name	Time	Method
Proportion of RCC among neoplastic and non-neoplastic renal lesions	From 2011 to 2020	Proportion of RCC among neoplastic and non-neoplastic renal lesions, strat-ified by investigated covariates (e.g., age, sex, smoking status, BMI, or hyper-tension treatment).

Trial Locations

Locations (1)

University Hospital Královské Vinohrady; 🇨🇿 Prague, Czechia