Interest of a 30 Minutes' Intermittent Work Exercise Test in Patients With Chronic Obstructive Pulmonary Disease: Cardiac and Pulmonary Functions
Not Applicable
Completed
- Conditions
- Pulmonary Disease, Chronic Obstructive
- Registration Number
- NCT00295113
- Lead Sponsor
- University Hospital, Strasbourg, France
- Brief Summary
The aim of the study is to observe the ventilatory and cardiac function (included the pulmonary arterial pressure) during an intermittent work exercise test with high density work load.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 10
Inclusion Criteria
- COPD patients (male and female) with moderate obstruction (FEV1/CV<60%)
Exclusion Criteria
- acute respiratory disease
- any type of cardiac disease
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method The pulmonary arterial pressure does not increase dramatically during the 30 minutes exercise test, but decreases significantly after the first 5 minutes of exercise.
- Secondary Outcome Measures
Name Time Method The cardiac output is stable after the first 5 minutes of exercise, despite the high intensity work loads every 5 minutes.
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms link intermittent exercise to pulmonary arterial pressure changes in COPD patients?
How does intermittent work exercise testing compare to standard spirometry in assessing COPD severity?
Are there specific biomarkers that correlate with cardiac function improvements during exercise in COPD?
What adverse events are associated with high-intensity intermittent exercise in COPD populations?
How do intermittent exercise protocols influence ventilatory efficiency in COPD compared to continuous exercise?
Trial Locations
- Locations (1)
Hôpitaux Universitaires de Strasbourg - Service des Explorations Fonctionnelles
🇫🇷Strasbourg, France
Hôpitaux Universitaires de Strasbourg - Service des Explorations Fonctionnelles🇫🇷Strasbourg, France