Relation of GREEN TEA with the prevention of CÂNCER OF THE LARGE INTESTNE AND RECTUM

Phase 2

Recruiting

• Conditions: K63.5; eoplasias Colorretais Hereditárias sem Polipose; Pólipo do cólon; C04.588.274.476.411.307.190

• Registration Number: RBR-63pc4t
• Lead Sponsor: A.C.Camargo Cancer Center

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-10-10
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Patients older than 20 years with Lynch syndrome with a mutation identified or meeting Amsterdam criteria will be included in the study with colonic colonoscopy of the screening colonoscopy; participants who agree to participate in the research by signing the Free and Informed Consent Form.

Exclusion Criteria

Presence of inflammatory bowel disease (such as ulcerative colitis and Crohn's disease); history of organ transplantation or co-administration of immunosuppressive drugs.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
It is expected to find a reduction in the onset of metachronic polyps within one year, verified by colonoscopy or rectosigmoidoscopy, with a 50% decrease after intervention.<br>

Secondary Outcome Measures

Name	Time	Method
It is expected to characterize as reliably as possible the relationship between the intake of green tea extract and the appearance of metachronic polyps with nutritional status, using body mass index and waist circumference in pre and post-intervention measurements.<br>;It is expected to characterize as reliably as possible the relationship between the eating habits of the patients in question and the appearance of metachronic polyps, using a validated food frequency questionnaire in pre and post-intervention measurements.<br>