Effects of Green Tea Supplementation after Fatty Meal in obese patients on change in blood inflammatio
Not Applicable
- Conditions
- ObesityE66.0
- Registration Number
- RBR-6b8rvt
- Lead Sponsor
- Faculdade de Medicina de Botucatu- Unesp
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- Not specified
- Target Recruitment
- Not specified
Inclusion Criteria
age greater than or equal to eighteen years and obesity (BMI greater than or equal to thirty kilograms per square meter).
Exclusion Criteria
Use of dietary supplements and systemic corticosteroids in the last three months, diagnosis of chronic non transmissible diseases such as hypertension, diabetes mellitus II, dyslipidemia, thyroid disease, neoplasms, coronary artery disease, stroke, heart failure, renal or hepatic failure and allergy to food offered in the survey.
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <br>Acute green tea supplementation reduces the inflammatory process (interleukin 6, TNFalpha and C-reactive protein, evaluated through commercially available kits and using the ELISA technique), reduce oxidative stress (concentrations of carbonyl groups based on the reaction with dinitrophenylhydralazine and the formation of the Schiff bases and malondialdehyde by high performance liquid chromatography) and modulate the expression of microRNAs (global expression performed through the ManqrayRodentMicroRNACards (A + B card sets v3.0) (Life Technologies) Taq platform).
- Secondary Outcome Measures
Name Time Method Secondary outcomes are not expected