ew way to treating the smile lines
- Conditions
- improvement of nasolabial fold by subcision.Procedure for purposes other than remedying health state, unspecified
- Registration Number
- IRCT201108097270N1
- Lead Sponsor
- Skin research center, Shohada-e-Tajrish hospital
- Brief Summary
The evaluation of efficacy and adverse effects of subcision in the correction of nasolabial fold <br /> <br /> Background. A prominent nasolabial fold (NLF) is a cosmetic problem. Currently, numerous therapeutic modalities are available<br /> for pronounced NLFs with variable efficacy. Objective. To determine the efficacy and safety of subcision using a hypodermic needle<br /> for the correction of the prominentNLFs and its effect on skin elasticity. Methods. Sixteen patients with prominentNLFs underwent<br /> subcision. The investigators’ assessment of improvement and the patients’ satisfaction were both recorded 1 and 6 months after the<br /> procedure. Also,we evaluate the skin elasticity of NLFs before and after the treatment using a sensitive biometrologic device with the<br /> measurement of cutaneous resonance running time (CRRT). Results. Thirteen (81.25%) patients showed a moderate improvement<br /> at 1stmonth and 13 (81.25%) patients had at least a mild improvement at 6th month. There was no persistent side effect lasting more<br /> than a few days. Mean CRRT at 1 and 6 months after the treatment was significantly higher compared to the baseline. Conclusion.<br /> Subcision may be considered effective for the correction of pronounced NLFs. However, further controlled studies with larger<br /> sample size are necessary to assess the efficacy of this technique in particular with use ofmore objective assessment of skin biometric<br /> characteristics. This trial is registered with IRCT201108097270N1 (registered on January 27, 2012).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 10
1. age 30-60y; 2.deep nasolabial fold. Exclusion criteria:1.age under 30y; 2.lactation & pregnancy; 3.history of coagulopathy or use of anticouagulant drug; 4.active infection in facial zone; 5.inability to stay in the study; 6.history of collagen or elastin disorder and connective tissue disease; 7.history of facial skin cancer; 8.history of topical medication administration during 1 month before study except sunscreen; 9.history of cosmetic procedure during last year (laser,..); 10. history of filler injection in nasolabial fold during last 5 years.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method asolabial fold. Timepoint: before treatment,1 w, 1 m and 6 m after treatment. Method of measurement: photograph,reviscometer.
- Secondary Outcome Measures
Name Time Method Bleeding. Timepoint: immediately after treatment and the day after. Method of measurement: observation.;Ecchymosis. Timepoint: 2 hours ,1 day and 1 week after treatment. Method of measurement: observation.;Infection. Timepoint: 1 w after treatment. Method of measurement: physical exam.