The Diagnosis and Treatment Pattern of CKD in Patients With Cardiovascular Disease- a National Cross-sectional Study

Recruiting

• Conditions: Renal Insufficiency, Chronic; Cardiovascular Diseases; Diagnosis

• Registration Number: NCT06143995
• Lead Sponsor: Guangdong Provincial People's Hospital

Brief Summary

The goal of this observational study is to learn about in a total of approximately 2000 patients with cardiovascular disease recruited from about 25 participating sites in China with eGFR\<60 ml/min/1.73 m2 and/or UACR\>30 mg/g at least twice 3 months apart within the previous 12 months who had been hospitalized in the cardiology department within the previous 12 months. The main questions it aims to answer are:

* To estimate the diagnosis rate of CKD in patients with cardiovascular disease and laboratory evidence of CKD

* To describe the CKD awareness and treatment pattern in patients with cardiovascular disease and laboratory evidence of CKD.

* To describe the socio-demographic and clinical characteristics of CKD in patients with cardiovascular disease and laboratory evidence of CKD

Participants will be invited to undergo a baseline visit, and the demographics, lifestyle factors, clinical characteristics, and laboratory tests will be collected.

Detailed Description

Not available

Study Timeline

• Status Verified: 2023-07
• Study Start: 2023-07-01
• Study First Submitted: 2023-08-20
• Study First Submitted QC: 2023-11-20
• Last Update Submitted: 2023-11-20
• Study First Posted: 2023-11-22
• Last Update Posted: 2023-11-22
• Primary Completion: 2024-07
• Study Completion: 2024-07

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 2000

Inclusion Criteria

1. Female and/or male aged ≥18 years
2. Admitted to the cardiology department with diagnosed cardiovascular disease within the previous 12 months
3. Participants with eGFR<60 ml/min/1.73 m2 and/or UACR>30 mg/g at least twice 3 months apart within the previous 12 months

Exclusion Criteria

1. Participants with known eGFR<20 ml/min/1.73 m2 or undergoing dialysis or kidney transplantation
2. Pregnant or lactating women
3. Exposure to contrast medium or other reason leading to potential acute kidney injury since the baseline examination of eGFR/UACR
4. Patients who were participating in or had participated in any other clinical trial within the previous 12 months

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
CKD diagnosis rates	1 day	CKD diagnosis rates in overall enrolled patients and subgroups (stratified by isolated estimated glomerular filtration rate (eGFR) measurement, isolated urinary albumin-to-creatinine ratio ( UACR) measurement, and both measurements) will be assessed in 12 month.

Secondary Outcome Measures

Name	Time	Method
Clinical characteristics	1 day	Clinical characteristics in the overall participants and groups stratified by CKD diagnosis (CKD diagnosis, and CKD non-diagnosis) will be reported in 12 months.
CKD diagnosis/treatment rate	1 day	CKD diagnosis/treatment rate in groups stratified by of disease types (HTN, Coronary artery disease (CAD), Heart Failure (HF), type 2 diabetes mellitus (T2DM), etc.) will be assessed in 12 months.
The number, types, treatment rates of medicine	1 day	The number, types, treatment rates of medicine (by class) for renal protection or with potential renal contraindication, awareness in the overall enrolled participants and groups stratified by CKD diagnosis (CKD diagnosis, CKD non-diagnosis) will be reported in 12 months.

Trial Locations

Locations (1)

Guangdong Provincial People's Hospital; 🇨🇳 Guangzhou, Guangdong, China