Acupuncture Combined With Nimodipine for Prevention of Post-stroke Dementia

Not Applicable

Completed

• Conditions: Post-stroke Dementia
• Interventions: Drug: The control group received oral nimodipine tablets

• Registration Number: NCT06007573
• Lead Sponsor: Yuzhen Pan

Brief Summary

To observe the clinical efficacy of TCM acupuncture combined with western medicine nimodipine for prevention of post-stroke dementia by comparing with clinical conventional treatment methods.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-02-01
• Status Verified: 2023-08
• Primary Completion: 2023-08-01
• Study Completion: 2023-08-15
• Study First Submitted: 2023-08-15
• Study First Submitted QC: 2023-08-22
• Last Update Submitted: 2023-08-22
• Study First Posted: 2023-08-23
• Last Update Posted: 2023-08-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

1. Definite ischemic stroke or hemorrhagic stroke confirmed by head CT / MRI examination
2. Memory or cognitive and executive dysfunction. Cognitive dysfunction will be determined after the mini mental state evaluation (MMSE) score
3. Age limited to 40-85 years, irrespective of gender
4. Stable condition, clear consciousness, no aphasia, oral medication available
5. No major comorbidity, no major depression
6. Consent and signed patient informed consent

Exclusion Criteria

1. Had serious medical conditions, such as heart, liver, kidney, or endocrine disease
2. Aphasia or hearing impairment
3. Participants in other clinical trials
4. Patients currently on medication to improve cognitive function

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
treatment group	The control group received oral nimodipine tablets	On the basis of the control group treatment, the treatment group also adopted the acupuncture treatment
control group	The control group received oral nimodipine tablets	The control group received oral nimodipine tablets

Primary Outcome Measures

Name	Time	Method
Response Rate	24 weeks

Secondary Outcome Measures

Name	Time	Method
Hasegawa Dementia Scale	24 weeks
Montreal Cognitive Assessment	24 weeks

Trial Locations

Locations (1)

The Second Affiliated Hospital of Anhui University of Chinese Medicine; 🇨🇳 Hefei, Anhui, China