Evaluation of the lung function using a new calculated index from ventilator settings, blood oxygen values, supplemented Oxygen fraction during assisted breathing and observed lung compliance, aiding early ventilator weaning and facilitating tracheal extubation after heart surgeries.
Not Applicable
- Conditions
- Health Condition 1: I251- Atherosclerotic heart disease of native coronary artery
- Registration Number
- CTRI/2023/01/048822
- Lead Sponsor
- HARI DEV J J
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Elective CABG, Aortic and Mitral valve surgeries with median sternotomy and two-lung ventilation.
2. Adult patients (age 18 years or older)
3. Ability to provide informed consent
Exclusion Criteria
1. Non-elective cardiac surgery
2. Patientâ??s refusal
3. Pregnancy
4. Thoracotomy approach, with one-lung ventilation
5. Previous pulmonary resection
6. Patients with acute kidney injury requiring dialysis
7. Patients with chronic kidney insufficiency (stage III or greater)
8. Patients already intubated before arrival in operating Théâtre.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary objectives: <br/ ><br>1.To evaluate the usefulness of the PaO2/FIO2Ã?PEEP ratio and Static lung compliance for <br/ ><br>predicting oxygenation status and ventilatory requirements after cardiac surgery in order to provide a <br/ ><br>potential tool and value for immediate postoperative assessment in fast-tracking. <br/ ><br>Timepoint: 7 months
- Secondary Outcome Measures
Name Time Method Secondary objectives: <br/ ><br>(d) To test the value of P/FP ratio and Static lung Compliance at 1hr post ICU <br/ ><br>admission in predicting postoperative pulmonary complications. <br/ ><br>(e) Evaluating P/FP ratio and Static lung compliance in predicting post extubation - <br/ ><br>NIV (Non Invasive Ventilation) requirement and duration. <br/ ><br>(f) To assess the correlation between P/FP ratio and Static lung compliance.Timepoint: 7 months