Erbium-YAG Laser Versus Platelet Rich Plasma in the Treatment of Atrophic Acne Scars

Not Applicable

Completed

• Conditions: Acne Vulgaris; Scars
• Interventions: Device: Fractional Erbium Yağ Laser; Procedure: Platelet Rich Plasma

• Registration Number: NCT03933033
• Lead Sponsor: Aswan University Hospital

Brief Summary

This study aim to assess the efficacy of Er-YAG laser 2940nm and PRP as a single line of treatment in comparison with combined treatment in atrophic post acne scars.

Detailed Description

Not available

Study Timeline

• Study Start: 2017-06-01
• Primary Completion: 2018-08-31
• Study Completion: 2019-02-28
• Status Verified: 2019-04
• Study First Submitted: 2019-04-25
• Study First Submitted QC: 2019-04-27
• Last Update Submitted: 2019-04-27
• Study First Posted: 2019-05-01
• Last Update Posted: 2019-05-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 75

Inclusion Criteria

• patients with atrophic post acne scars classified on the basis of Goodman and Baron's Qualitative classification, no active acne lesions and patients with atrophic scars only

Exclusion Criteria

• patients with positive history of keloidal tendency, positive history of bleeding tendency, platelet disorder, patients with any acute infection on face like, herpes, folliculitis, patients with HIV, HBsAg, patients with a history of autoimmune diseases or patients on immunosuppressive drugs.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Group C	Fractional Erbium Yağ Laser	treated with both line of treatments
Group B	Fractional Erbium Yağ Laser	treated with Erbium Yag Laser
Group A	Platelet Rich Plasma	treated with platelet rich plasma
Group C	Platelet Rich Plasma	treated with both line of treatments

Primary Outcome Measures

Name	Time	Method
Change in grade of acne scares according toQualitative scarring grading system of Goodman and Baron	6 months	Grade of acne scares improvement after treatment
Change in patient satisfaction usinga four-point scale; Grade 4 highly satisfied, Grade 3 satisfied, Grade 2 neutral and Grade 1 dissatisfied	6 month	increase in patient satisfaction after treatment
Change in clinical appearance of acne scare accordinga four-point scale for assessment of clinical improvement of skin smoothness	6 month	improvement of acne scares as evaluated by sequential photos

Trial Locations

Locations (1)

Aswan University Hospital; 🇪🇬 Aswan, Egypt