Erbium-YAG Laser Versus Platelet Rich Plasma in the Treatment of Atrophic Acne Scars
Not Applicable
Completed
- Conditions
- Acne VulgarisScars
- Registration Number
- NCT03933033
- Lead Sponsor
- Aswan University Hospital
- Brief Summary
This study aim to assess the efficacy of Er-YAG laser 2940nm and PRP as a single line of treatment in comparison with combined treatment in atrophic post acne scars.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 75
Inclusion Criteria
- patients with atrophic post acne scars classified on the basis of Goodman and Baron's Qualitative classification, no active acne lesions and patients with atrophic scars only
Exclusion Criteria
- patients with positive history of keloidal tendency, positive history of bleeding tendency, platelet disorder, patients with any acute infection on face like, herpes, folliculitis, patients with HIV, HBsAg, patients with a history of autoimmune diseases or patients on immunosuppressive drugs.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Change in grade of acne scares according toQualitative scarring grading system of Goodman and Baron 6 months Grade of acne scares improvement after treatment
Change in patient satisfaction usinga four-point scale; Grade 4 highly satisfied, Grade 3 satisfied, Grade 2 neutral and Grade 1 dissatisfied 6 month increase in patient satisfaction after treatment
Change in clinical appearance of acne scare accordinga four-point scale for assessment of clinical improvement of skin smoothness 6 month improvement of acne scares as evaluated by sequential photos
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular pathways does Erbium-YAG laser 2940nm activate in atrophic acne scar remodeling?
How does fractional Er-YAG laser compare to PRP in collagen synthesis and scar reduction efficacy?
Which biomarkers correlate with response to PRP therapy in atrophic acne scar patients?
What are the adverse event profiles of Er-YAG laser and PRP for facial scar treatment?
Are combination therapies of Er-YAG laser and PRP superior to monotherapies in NCT03933033?
Trial Locations
- Locations (1)
Aswan University Hospital
🇪🇬Aswan, Egypt
Aswan University Hospital🇪🇬Aswan, Egypt