A clinical study to find the duration of postoperative pain relief between two drugs, Dexmedetomidine and Buprenorphine which are given before the surgery through a needle near shoulder in healthy patients undergoing upper limb surgery.
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2024/07/071614
- Lead Sponsor
- IRANCHAN RAMANATHA
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Patients aged between 18 to 65 years who are posted for Upper limb surgeries.
2.American Society of Anaesthesiologists (ASA) physical Status I and II patients.
Exclusion Criteria
1.Patients who refuse to give informed written consent.
2.Patients who are medically unstable.
3.Patients with deranged coagulation profile.
4.Patients who are addicted to narcotics.
5.Patients who are allergic to levobupivacaine, ropivacaine, Dexmedetomidine.
6.Pregnant women
7.Patients on opioid medications.
8.Neurological and musculoskeletal disease.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Assessment of Visual Analogue Scale (VAS) to calculate the duration of Pain relief. Rescue analgesia will be given when VAS score was more than or equal to 4.Timepoint: Baseline Visual Analogue Score (VAS) is measured from the time patient is admitted at Postoperative ward and every 60 minutes for next 24 hours.
- Secondary Outcome Measures
Name Time Method To assess the Onset & Duration of sensory & motor blockade, intraoperative & intraoperative Hemodynamics & Sedation. <br/ ><br>Timepoint: Onset of sensory blockade is defined by a score of 1 on pinprick response. <br/ ><br>Onset of motor blockade will be the complete motor paralysis of wrist & hand. <br/ ><br>Hemodynamic parameters will be monitored using routine monitors used during a Surgery. <br/ ><br>Baseline is measured from the end of the intervention & every 5 minutes after that for next 30 minutes.