A clinical trial to study the effects of two pain relief drugs, dexmedetomidine and buprenorphine added to levobupivacaine, a numbing drug injected below the curved front bone of the shoulder using an imaging machine in patients undergoing broken bone surgeries of upper extremity.
Not Applicable
- Conditions
- Health Condition 1: PCS- Health Condition 2: O- Medical and Surgical
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
ASA physical status I or II patients
Age 18â??60 years, scheduled for surgeries of the forearm, wrist and hand under US-guided infraclavicular brachial plexus block
Exclusion Criteria
Patients aged <18 years or >60 years.
Patients having body weight <40 kg and >70 Kg.
Any contraindication to regional anesthesia.
Refusal for infraclavicular block and inability to give consent
Patients undergoing surgeries of arm, elbow, shoulder
Patients having peripheral neuropathy or hypersensitivity to local anaesthetic agents.
Patients having history of seizures.
History of pulmonary, cardiac, hematological, endocrinal, and neuromuscular disorders.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method post operative analgesia using VAS pain scaleTimepoint: postoperative period 2nd,4th,6th,8th,12th,16th,20th,24th,28th,32nd,36th,40th,44th,48th hour
- Secondary Outcome Measures
Name Time Method Anticipated side effectsTimepoint: post operative period upto 48 hours;Hemodynamic parameters ( Heart rate, respiratory rate, systolic blood pressure,diastolic blood pressure, mean arterial pressure, oxygen saturation)Timepoint: baseline, 2 minutes, 4 minutes, 6 minutes, 8 minutes, 10 minutes, 15 minutes, 30 minutes, 45 minutes, 1 hour, 1.5 hours, 2 hours, 4 hours, 6 hours, 8 hours, 10 hours, 12 hours, 16 hours, 20 hours, 24 hours, 28 hours, 32 hours, 36 hours, 40 hours, 44 hours, 48 hours;Motor block ( onset of motor blockade and return to bromage score 0)Timepoint: post operative period upto 48 hours;Sensory block(complete loss of sensation to pin prick to return of sensation)Timepoint: post operative period upto 48 hours