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Identification of diagnostic biomarkers in tubercular uveitis patients.

Not Applicable
Conditions
Health Condition 1: H438- Other disorders of vitreous body
Registration Number
CTRI/2023/06/053753
Lead Sponsor
Indian Council of Medical Research (ICMR), New Delhi
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Open to Recruitment
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

Cases of tubercular or suspected tubercular posterior uveitis satisfying definition of ‘persistent’, ‘severe’ or ‘atypical’ presentation.

-Cases of idiopathic macular hole, non-inflammatory ERM and RRD posted for vitrectomy (negative controls)

-Cases of clinical endophthalmitis planned for vitrectomy (positive control).

Exclusion Criteria

-Patients not consenting for the study.

-Pregnant lady

-Age below 18 years

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Any suitable biomarker protein after validation with the described techniques can be further used in the development of an early diagnostic ELISA kits or rapid diagnostic kits & can be used as potential drug targets.Timepoint: After completion of whole study as well as data analysis we will be able to find a protein of interest that may be further taken to prepare an early diagnostic ELISA kit or rapid diagnostic kit.
Secondary Outcome Measures
NameTimeMethod
ilTimepoint: Nil
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