The effect of melatonin on Cardiac Enzymes after Cardiac surgery

Phase 3

Recruiting

Conditions: coronary artery bypass graft (CABG) surgery.
Unspecified complication of cardiac and vascular prosthetic device, implant and graft

Registration Number: IRCT20141006019417N2

Lead Sponsor: Qazvin University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 100

Inclusion Criteria

18 to 80 years old patients who are candidates for coronary artery bypass graft;
Informed consent to participate in the study.

Exclusion Criteria

Taking anticonvulsants - antidepressants drugs;
History of coronary artery bypass graft;
Emergency Coronary Artery Bypass Grafting;
Ejection Fraction ? 30;
Severe pulmonary disease;
Non-sinus rhythm heart before surgery;
Having a pacemaker;
Liver disease;
Simultaneously valvular heart surgery.

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Biomarkers( Erythrocyte Sediman Rate, C-Reactive Protein, Troponin I & CPK-MB). Timepoint: On six hours after entering the ICU and the second & third day after surgery. Method of measurement: Laboratory kits.

Secondary Outcome Measures

Name	Time	Method
Arrhythmia. Timepoint: Length of Stay for Critical Care Admissions. Method of measurement: Patient file.;Length of Stay for Critical Care Admissions. Timepoint: Total number of days the ICU. Method of measurement: Patient file.;The number of days spent in hospital after breast cancer surgery. Timepoint: Discharge day from hospital. Method of measurement: Patient file.