Open labelled, single arm, interventional study of topical dutasteride lotion for androgenetic alopecia.

Not Applicable

Completed

• Conditions: Health Condition 1: L649- Androgenic alopecia, unspecified

• Registration Number: CTRI/2022/04/041637
• Lead Sponsor: CUTIS Academy of Cutaneous Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2022-09-07
• Last Update Posted: 21 November 2022

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 10

Inclusion Criteria

1.All patients aged 18 - 60 years diagnosed with mild to moderate androgenetic alopecia attending the OPD (Norwood Hamilton scale III to V and Ludwig scale II and III)

2.Patients willing to refrain from other forms of treatment including other topical medications, oral medications for hair loss (other than the nutritional supplement prescribed), laser treatments, injectable treatments and hair transplantation for the duration of the study.

3.Women of child-bearing age with FPHL, who are not planning pregnancy in the next 2 years and are willing to give consent stating the same.

4.Patients who are willing to appear for regular follow ups and follow the prescribed treatment regularly.

Exclusion Criteria

1.Patients suffering from other causes of non-cicatricial alopecia or cicatricial alopecia.

2.Patients suffering from infectious, auto-immune, or other disorders affecting skin of scalp.

3.Patients already on drugs that would affect the hair cycle in past 3 months.

4.Patients suffering from severe AGA (Norwood Hamilton scale VI to VII).

5.Women of child-bearing age planning pregnancy in the next 2 years.

6.Patients known to be allergic to any of the components of the study medications.

7.Patients with known malignancy or those on chemotherapy.

8.Refusal to participate in the study.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To know the efficacy of topical dutasteride lotion in the treatment of <br/ ><br>androgenetic alopecia. <br/ ><br>Parameters assessed - Increase in Hair density and Increase in Terminal: Vellus hair ratio <br/ ><br>Assessment of global photographs and Trichoscopy images will be doneTimepoint: After 3 months

Secondary Outcome Measures

Name	Time	Method
Clinical photographs â?? taken in same position and with uniform illumination. Grading of Hair loss â?? Norwood Hamilton, Ludwigâ??s grading. Trichoscopy with video-dermoscope (Fotofinder) before and at the end of study period (Day 0 and Day 90) to analyse the outcome.Timepoint: After 3 months