Neuromodulation of Executive Function in the ADHD Brain
- Conditions
- Attention Deficit Hyperactivity Disorder
- Registration Number
- NCT04175028
- Lead Sponsor
- Massachusetts General Hospital
- Brief Summary
This study aims to determine the transient, modulatory effects of transcranial direct current stimulation (tDCS) on executive function and inhibitory control in patients with ADHD compared to healthy controls.
- Detailed Description
This study aims to determine the transient, modulatory effects of transcranial direct current stimulation (tDCS) on executive function and inhibitory control in patients with ADHD. Deficits in these cognitive functions are core to ADHD, and cause significant impairment and morbidity. The study will also include a cohort of healthy controls for comparison.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 120
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method Change in Accuracy and Reaction Time in Inhibition/Decision Making Change Before and After Stimulation on Each of the Three Visits, Average 2-6 Weeks Cambridge Gambling Task
Change in Accuracy and Reaction Time in Attention and Working Memory Change Before and After Stimulation on Each of the Three Visits, Average 2-6 Weeks Multi-Source Interference with International Affective Picture System Task
- Secondary Outcome Measures
Name Time Method Amplitude of Encephalogram (EEG) Event Related Potentials Change Before and After Stimulation on Each of the Three Visits, Average 2-6 Weeks Measure of amplitude related to stimulus
Trial Locations
- Locations (1)
Massachusetts General Hospital
🇺🇸Boston, Massachusetts, United States
Massachusetts General Hospital🇺🇸Boston, Massachusetts, United StatesBlake Andreou, BSContact617-724-8780bandreou@mgh.harvard.edu