Prospective study of venous thromboembolism and bleeding complications associated with primary and secondary VTE prevention during pregnancy and postpartum in women with previous VTE, hereditary thrombophilia or antiphospholipid syndrome

Recruiting

• Conditions: O22.3; D68.5; Deep phlebothrombosis in pregnancy; Primary thrombophilia

• Registration Number: DRKS00028688
• Lead Sponsor: niversitätsklinikum RegensburgUniversitäres Gefäßzentrum - Bereich Angiologie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-04-05
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 1000

Inclusion Criteria

Pregnancy in the 1st/2nd trimester and previous VTE with 1. terminated or ongoing anticoagulation, 2. hereditary thrombophilia without previous VTE or 3. antiphospholipid syndrome

Exclusion Criteria

none

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Symptomatic deep vein thrombosis, superficial vein thrombosis, atypical thrombosis and/or pulmonary embolism; major bleeding according to ISTH definition

Secondary Outcome Measures

Name	Time	Method
Clincial relevant non-major bleeding according to ISTH definition; arterial thrombosis, allergic skin reaction, heparin-induced thrombocytopenia, bone fractures, early and late abortions, preterm birth, praeeclampsia, eclampsia, fetal birth defect