Effect of intravenous ketamine infusion on obstetric quality of recovery score in patient undergoing cesarean delivery after spinal anesthesia: A randomized, triple-blinded, controlled trial

This is a study measuring patient centered outcome to guide meaningful changes in obstetric anesthesia care. The obstetric quality of recovery score provides a holistic measure of patient reported recovery for mother undergoing cesarean delivery, comprising both psychological and functional outcomes. In this study we have planned to determine effectiveness of low dose ketamine infusion in patient receiving spinal anesthesia for lower uterine section.

Primary Objective is to compare OBS Q0R11 score in patient receiving low dose ketamine infusion vs control group at 24 hours time period point in post operative period.

Secondary Objective are hemodynamic parameter, post operative pain assessed by VAS score, sedation score, fetus evaluated by APGAR score, post operative nausea, vomiting, nystagmus, diplopia and hallucination, Ramsay sedation score, perioperative shivering.

Type of study is randomized, triple blind, prospective, controlled study.

Inclusion criteria comprises of full term female patient between 21 and 41 with ASA I, II, III.

Exclusion criteria comprises of twins and preterm birth, hypertensive and pre eclampsia patient, morbidly obese patient, spinal anesthesia contraindication because the patient refused, severe mitral and tricuspid stenosis and local infection

The patient would be equally randomized into two groups. One group will be given intravenous ketamine and the other group will be given intravenous saline. OBSQ0R11 scale at 24 hours in post operative will be seen

Sample size is 142.