To compare efficacy of intravenous ketamine-propofol versus ketamine -dexmedetomidine in adult patient undergoing daycare procedure
Trial Snapshot
- Phase
- Phase 4
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- 1)To compare the demand of rescue anaesthetic during procedure.
Study Overview
Brief Summary
This study aims to contribute to existing literature by comparing the efficacy of intravenous ketamine- propofol versus ketamine dexmedetomedine in adult patient undergoing daycare procedure .the main focus is to evaluate the need of rescue bolus required after infusion , time taken to achive adeqaute sedation and effective sedation . through this research , we strive to provide valuable insights aimed at safer and more efficacious choice for procedural sedation in short surgical procedure.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Masking
- None
Eligibility Criteria
- Ages
- 18.00 Year(s) to 65.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •ASA Physical status I or II Scheduled for elective daycare procedure willing and able to provide written consent BMI between 18.5 to 29.9 Procedure duration less than 60 minutes.
Exclusion Criteria
- •known allergy to any of study drug 2)history of cardiovascular, hepatic, renal or psychiatric disorder 3)pregnancy or lactation 4)chronic use of sedative or opioids.
Outcomes
Primary Outcomes
1)To compare the demand of rescue anaesthetic during procedure.
Time Frame: Time from start of infusion to achieve RSS 5 | ( ramsay sedation score ) | from start of infusion , patient movement will be noted. if any movement is seen , that time will be documented.
2)2) To compare time require to achieve adequate and effective sedation for procedure ( Ramsay sedation score 5 ) between the study groups.
Time Frame: Time from start of infusion to achieve RSS 5 | ( ramsay sedation score ) | from start of infusion , patient movement will be noted. if any movement is seen , that time will be documented.
Secondary Outcomes
- ) To compare the time to eye opening after cessation of infusion of study drugs between study groups.(2) To compare the recovery time between the two study groups)
Investigators
Mehak
Adesh institute of medical science and research