Comparison of Gadobutrol and Gadobenate Dimeglumin for Delayed Enhancement Cardiac MRI
Phase 2
Completed
- Conditions
- Subacute/Chronic Myocardial Infarction
- Registration Number
- NCT01655290
- Lead Sponsor
- Technical University of Munich
- Brief Summary
This study aims at evaluating the diagnostic efficacy of Gadobutrol versus Gadobenate dimeglumine at similar dose of 0.1mmol/kg for assessment of myocardial infarction by delayed enhancement cardiac Magnetic Resonance Imaging
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
- Diagnosis of myocardial infarction
- Age ≥ 18 years and ≤ 80 years
- Informed consent
- Male patients as well as female patients using contraceptives
Exclusion Criteria
- Patients with a heart pacemaker, with magnetic material or other magnetic implants.
- Renal failure (GFR <30ml/min)
- Patients with known allergy to a Gadolinium-containing contrast agent
- Drugs or alcohol addiction, dementia
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method Efficacy (contrast-to-noise ratio)
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms differentiate Gadobutrol and Gadobenate Dimeglumin in delayed enhancement cardiac MRI for chronic myocardial infarction?
How does the diagnostic accuracy of Gadobutrol compare to Gadobenate Dimeglumin for assessing myocardial scar tissue at 3 Tesla MRI?
What biomarkers correlate with improved imaging outcomes in NCT01655290 for subacute/chronic myocardial infarction using GBCAs?
What are the safety profiles of Gadobutrol versus Gadobenate Dimeglumin in cardiac MRI for patients with chronic myocardial infarction?
How do Gadobutrol and other gadolinium-based contrast agents compare in detecting myocardial fibrosis in post-infarction patients?
Trial Locations
- Locations (1)
Institut für Radiologie - Klinikum Rechts der Isar
🇩🇪Munic, Bavaria, Germany
Institut für Radiologie - Klinikum Rechts der Isar🇩🇪Munic, Bavaria, Germany