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Rehabilitation After Admission in Intensive Care Unit for COVID-19

Completed
Conditions
Covid19
Registration Number
NCT04523051
Lead Sponsor
Centre Hospitalier Régional Metz-Thionville
Brief Summary

France and especially the region "Grand Est" have been severely impacted by the COVID-19 pandemic. The first affected patients gradually began leaving the hospitalization sector and some of them required rehabilitation before returning home.

Because it has only been studied for few months, COVID 19 possible impairment remain unknown, especially in patients who required admission in ICU and needed rehabilitation.

In order to better understand the impact of the disease, the investigators wish to carry out a descriptive analysis of hospitalized patient in rehabilitation center for Post-Covid-19 rehabilitation after ICU.

The purpose of this study was to describe the impairments and functional independency in patients addressed to a rehabilitation center after an ICU stay for COVID 19 and to explore the factors associated with their evolution.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
39
Inclusion Criteria
  • Post-COVID patient hospitalized in rehabilitation center
  • Admission in Intensive Care Unit with proven COVID-19 disease before
Exclusion Criteria
  • Patients not willing to participate via using their medical files

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Functional Independence measure (FIM) at the admissionDay 1

The FIM is an 18-item clinician-reported scale that assesses function in six areas including self-care, continence, mobility, transfers, communication and cognition. Each of the 18 items is graded on a scale of 1-7 based on level of independence in that item (1=total assistance required, 7=complete independence).

Functional Independence measure (FIM) 1-month hospitalizationDay 30

The FIM is an 18-item clinician-reported scale that assesses function in six areas including self-care, continence, mobility, transfers, communication and cognition. Each of the 18 items is graded on a scale of 1-7 based on level of independence in that item (1=total assistance required, 7=complete independence).

Functional Independence measure (FIM) at the dischargeDay 180

The FIM is an 18-item clinician-reported scale that assesses function in six areas including self-care, continence, mobility, transfers, communication and cognition. Each of the 18 items is graded on a scale of 1-7 based on level of independence in that item (1=total assistance required, 7=complete independence).

Secondary Outcome Measures
NameTimeMethod
SexDay 1

gender of participants

Oxygen saturation of the blood at the admissionDay 1

The measuring of oxygen saturation of the blood by means of an oximeter at the admission

Estimated functional independence measure score before Covid-19Day 1

The FIM is an 18-item clinician-reported scale that assesses function in six areas including self-care, continence, mobility, transfers, communication and cognition. Each of the 18 items is graded on a scale of 1-7 based on level of independence in that item (1=total assistance required, 7=complete independence). Estimating the functional independence score before the disease.

Length of stay in acute careDay 1

Length of stay in acute care for Covid-19

Length of stay in rehabilitation centersDay 180

Length of stay in rehabilitation centers

weight at the dischargeDay 180

weight of the patient after hospitalization

Dyspnea symptoms at the admissionDay 1

Dyspnea symptoms according to the modified Medical Research Council (mMRC) scale. The mMRC is a self-rating tool to measure the degree of disability that breathlessness poses on day-to-day on a scale from 0 to 4 (0= no breathlessness except on strenuous exercise and 4= too breathless to leave the house, or breathless when dressing or undressing

weight at admissionDay 1

weight of the patient

Length of stay in ICU unitDay 1

Length of stay in ICU unit for Covid-19

Joint limitationDay 1

Presence of joint limitation during the management

Functional exercise capacityDay 1

Functional exercise capacity measured by a 6 minutes Walking test

Neurological examination at the dischargeDay 180

presence of anosmia, dysgeusia, swallowing disorders, phonation disorders, phasic disorders, confusion, headache, urinary or fecal incontinence at the discharge

ageDay 1

age of the patient at the admission in rehabilitation center

Presence of pressure ulcersDay 180

Presence of pressure ulcers, stage and localization during the management of patient

Risk of bedsoreDay 1

Risk of bedsore with the Braden scale. The Braden score consists of six subscales (sensory perception, moisture, activity, mobility, nutrition and friction/shear) representing the most commonly occuring risk factors for pressure ulcers and is scored from 6 to 23, with lower scores representing higher risk of developing pressure ulcers.

Dominant sideDay 1

Dominant side of the patient

Presence of psychic disordersDay 180

Presence of psychic disorders like delirium, sleep disorders, anxiety, sadness of mood, loss of appetite, suicidal thoughts, asking for psychologist care during the stay

Estimated dyspnea symptoms before Covid-19Day 1

The modified Medical Research Council (mMRC) scale is a self-rating tool to measure the degree of disability that breathlessness poses on day-to-day on a scale from 0 to 4 (0= no breathlessness except on strenuous exercise and 4= too breathless to leave the house, or breathless when dressing or undressing).

Length of Invasive mechanical ventilationDay 1

Length of Invasive mechanical ventilation during the stay

Muscle strength at the admissionDay 1

Muscle strength examination according to Medical Research Council muscle strength scale. This scale involves testing key muscles from the upper and lower extremities against the examiner's resistance and grading the patient's strength on a 0 to 5 scale with 0= no muscle activation and 5= muscle activation against examiner's full resistance, full range of motion.

Muscle strength at the dischargeDay 180

Muscle strength examination according to Medical Research Council muscle strength scale. This scale involves testing key muscles from the upper and lower extremities against the examiner's resistance and grading the patient's strength on a 0 to 5 scale with 0= no muscle activation and 5= muscle activation against examiner's full resistance, full range of motion.

Dyspnea symptoms at the dischargeDay 180

Dyspnea symptoms according to the modified Medical Research Council (mMRC) scale. The mMRC is a self-rating tool to measure the degree of disability that breathlessness poses on day-to-day on a scale from 0 to 4 (0= no breathlessness except on strenuous exercise and 4= too breathless to leave the house, or breathless when dressing or undressing

Destination of patients at dischargeDay 180

Destination of patients at discharge from rehabilitation center. For the destination there is 4 possibility: the return home, institutionalization, re-hospitalization or other (specify where).

Oxygen saturation of the blood at the dischargeDay 180

The measuring of oxygen saturation of the blood by means of an oximeter at the discharge

Presence of Hoffman signsDay 180

Hoffman's sign is a test to examine the reflexes of the upper extremities.

Presence of Babinski signsDay 180

The Babinski reflex is obtained by stimulating the external portion of the sole.

Neurological examination at the admissionDay 1

presence of anosmia, dysgeusia, swallowing disorders, phonation disorders, phasic disorders, confusion, headache, urinary or fecal incontinence at the admission

Trial Locations

Locations (3)

Etablissement de santé Filieris

🇫🇷

Freyming-Merlebach, Moselle, France

Hopital Legouest

🇫🇷

Metz, Moselle, France

CHR Metz Thionville

🇫🇷

Metz, Moselle, France

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