COVID-19 Critically Ill Patients' Evolution After Medical Transport by Train From Paris Intensive Care Units to West of France Intensive Care Units

• Conditions: Intensive Care Unit Syndrome; COVID-19

• Registration Number: NCT04433325
• Lead Sponsor: Rennes University Hospital

Brief Summary

Since early 2020, France knows a sanitary crisis with a massive influx of COVID-19 patients admitted in Intensive Care Units (ICU). It led to a saturation of the French health system, especially in some geographic areas such as East of France or Paris region. Therefore, authorities decided to transfer some critically ill patients from these crowded ICUs to less busy regional ICUs. it was done for the first time by medical train transportation. Knowing that the investigators lack experience regarding this type of medical evacuation, regarding the high number of transferred patients, with such a logistic effort, the investigators decided to study this phase of the COVID-19 sanitary crisis in order to draw a feedback. So far, there are no data in the literature regarding this topic.

Detailed Description

Not available

Study Timeline

• Status Verified: 2020-06
• Study Start: 2020-06
• Study First Submitted: 2020-06-12
• Study First Submitted QC: 2020-06-15
• Last Update Submitted: 2020-06-15
• Study First Posted: 2020-06-16
• Last Update Posted: 2020-06-16
• Primary Completion: 2020-07
• Study Completion: 2020-09

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

• Age > 18 years
• COVID-19 positive patients admitted in Intensive Care Unit between 15/03/2020 and 15/04/2020
• Patients (or legal representative) with no opposition to inclusion in medical research protocol
• Regarding case group : Patients transferred from Paris's ICU
• Regarding case control group : Patients admitted in ICU with no transfer from Paris

Exclusion Criteria

• > 18 years under legal protection and patients with liberty restriction

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
number of death	at Intensive Care Units discharge, an average of 1 months	to evaluate mortality

Secondary Outcome Measures

Name	Time	Method
number of days of vasopressor use	from date of admission until Intensive Care Units discharge, assessed up to 1 months
number of days in Intensive Care Units	from date of admission until Intensive Care Units discharge, assessed up to 1 months
number of infections	from date of admission until Intensive Care Units discharge, assessed up to 1 months	to evaluate morbidity
number of days of mechanical ventilation	from date of admission until Intensive Care Units discharge, assessed up to 1 months
number of days of sedation	from date of admission until Intensive Care Units discharge, assessed up to 1 months
number of days of use of neuromuscular blocking agents	from date of admission until Intensive Care Units discharge, assessed up to 1 months
number of days in hospital	from date of admission until hospital discharge, assessed up to 1 months

Trial Locations

Locations (2)

CHU Poitiers; 🇫🇷 Poitiers, France

CHU Tours; 🇫🇷 Tours, France