sing Positron Emission Tomography Scan (PET scan) to improve diagnosis of pulmonary embolism.

Not Applicable

Recruiting

• Conditions: Malignancy; Pulmonary embolism; Blood - Clotting disorders; Cancer - Any cancer; Respiratory - Other respiratory disorders / diseases

• Registration Number: ACTRN12614001170617
• Lead Sponsor: Peter MacCallum Cancer Center

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-11-06
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Patient with suspected acute pulmonary embolism
Patient has diagnosis of malignancy
Age greater than or equal to 18 years;
Written informed consent has been provided.

Exclusion Criteria

Contraindication to contrast media (including renal insufficiency with eGFR<50)
Participant is not able to tolerate supine position for PET/CT acquisition, is not cooperative, or needs continuous nursing (e.g. patient from Intensive Care Unit).
Inability to perform CTPA and V/Q PET/CT within the 24 hours following the suspicion of PE.
Deep vein thrombosis or PE diagnosed within the previous 3 months
Use of therapeutic doses of parenteral anticoagulants for greater than 48 hours
Pregnancy
Breast-feeding

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Diagnosis of pulmonary embolism classified as present, indeterminate or not present assessed with CTPA alone and with V/Q PET/CT alone.<br>[Single time-point];Diagnosis of pulmonary embolism classified as present, indeterminate or not present assessed with combined V/Q PET / CTPA[Single time-point]

Secondary Outcome Measures

Name	Time	Method
Detection of anomalies on CTPA only, V/Q PET/CT only, and both combined.[Single time-point]