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Clinical Trials/CTRI/2025/07/089993
CTRI/2025/07/089993
Not yet recruiting
Not Applicable

"Efficacy of Combined Paracetamol and Dexamethasone Analgesia in Postoperative Pain Management Following ENT Surgery: A Randomized Controlled Trial."

SRI RAMACHANDRA UNIVERSITY1 site in 1 country72 target enrollmentStarted: July 11, 2025Last updated:
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Overview

Phase
Not Applicable
Status
Not yet recruiting
Sponsor
SRI RAMACHANDRA UNIVERSITY
Enrollment
72
Locations
1
Primary Endpoint
Postoperative pain score
OverviewStudy DesignEligibility CriteriaOutcomesInvestigatorsSitesRecords & IdentifiersSimilar Trials

Overview

Brief Summary

Paracetomol and dexamethasone are both used in postoperative pain management,but they both work through different mechanism.Paracetomol is an analgesic that reduces pain and dexamethasone is a corticosteroid that reduces inflammation by the way it helps in encountering postoperative pain and nausea vomiting.Combining both the drugs will be effective than using either drug alone ,potentially leading to better pain control and reducing opioid requirement and antiemetic use

Study Design

Study Type
Interventional
Allocation
Randomized
Masking
Participant and Investigator Blinded

Eligibility Criteria

Ages
18.00 Day(s) to 60.00 Day(s) (—)
Sex
All

Inclusion Criteria

  • •Asa 1 and 2 All elective ENT surgeries done under general anaesthesia.

Exclusion Criteria

  • •Patient refusal to give consent Allergy to paracetamol and dexamethasone Emergency cases Patients on steroid therapy Patients having condition for which paracetamol cand dexamethasone contraindicated ASA 4 and ASA 5.

Outcomes

Primary Outcomes

Postoperative pain score

Time Frame: Postoperative pain score

Secondary Outcomes

  • POSTOPERATIVE NAUSEA VOMITING(NO OF POSTOPERATIVE ANALGESIC REQUIREMENT)

Investigators

Sponsor
SRI RAMACHANDRA UNIVERSITY
Sponsor Class
Research institution and hospital
Responsible Party
Principal Investigator
Principal Investigator

Dr Ramya

Sri Ramachandra institute of medical sciences and research institutes

Study Sites (1)

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