A prospective randomized comparative study of dexamethasone versus magnesium sulphate as an adjuvant to ropivacaine in ilioinguinal iliohypogastric block in lower abdominal surgeries under general anaesthesia.
Overview
- Phase
- Phase 2/3
- Status
- Not yet recruiting
- Sponsor
- LLRM Medical College
- Enrollment
- 80
- Locations
- 1
- Primary Endpoint
- To evaluate and compare the efficacy and the
Overview
Brief Summary
This is a prospective randomised comparative evaluation of postoperative analgesia achieved with Ilioinguinal Iliohypogastric block using Ropivacaine with Dexamethasone versus Ropivacaine with Magnesium Sulphate in lower abdominal surgeries performed under general anaesthesia.
Also will be assessing the timing of requiring first dose of rescue analgesic, total dose of rescue analgesia required in 24 hours, hemodynamic changes, Quality of Recovery Score assessment and complications if any during post operative period.
Study Design
- Study Type
- Interventional
- Allocation
- Other
- Masking
- Participant and Investigator Blinded
Eligibility Criteria
- Ages
- 18.00 Year(s) to 65.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •ASA Grade 1 And 2 Age 18-65 Yrs Sex Male and Female BMI 18 to 25 kg per sq metre Patients Undergoing lower abdominal surgeries under General Anaesthesia Patients with informed consent.
Exclusion Criteria
- •Patient refusal Infection at injection site Coagulopathy Significant cardiopulmonary diseases, hepatic and renal dysfunction Chronic alcohol or narcotic drug abuse Peripheral neuropathy Known allergy or hypersensitivity to study drug.
Outcomes
Primary Outcomes
To evaluate and compare the efficacy and the
Time Frame: Postoperatively pain will be assessed at different | time intervals for initial 24 hrs
quality of post operative analgesia.
Time Frame: Postoperatively pain will be assessed at different | time intervals for initial 24 hrs
Secondary Outcomes
- Timing of requiring first dose of rescue analgesic(Patient to be assessed for 24 hours post)
- Total analgesic consumption in 24 hours(Patient to be assessed for 24 hours post)
- Assess hemodynamic changes(Patient to be assessed for 24 hours post)
- Post operative Quality of Recovery Score(Patient to be assessed for 24 hours post)
Investigators
Dr Shivangi Gupta
Lala Lajpat Rai Memorial Medical College Meerut