Comparison between the efficacy of intravenous dexmedetomidine vs intravenous lignocaine on post operative analgesia in patients undergoing laparoscopic cholecystectomy
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 86
- 试验地点
- 1
- 主要终点
- 1) Duration of analgesia
研究概览
简要总结
This is a prospective observational study to compare intraoperative hemodynamic stability and postoperative analgesia using Intravenous lignocaine vs intravenous dexmedetomidine in patients undergoing laparoscopic cholecystectomy. The study is planned to be conducted at a tertiary hospital in Dakshina Kannada. The study will be carried out on patients aged 18 to 65 years of ASA grade I and II undergoing laparoscopic cholecystectomy. The study has already cleared the institutional ethics committee approval.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients aged 18 to 65 years of either sex with the American Society of Anesthesiologists physical status classes 1 and 2 undergoing elective laparoscopic cholecystectomy surgery.
排除标准
- •Patients unwilling to participate in the study.
- •Patients with BMI more than 35 kgm2 3)History of hypersensitivity to the drugs 4)Parturient 5)Chronic use of opioids or opioid addiction, steroids.
- •Inability to comprehend postoperatively for the pain assessment scale or neuropsychiatric disorders.
结局指标
主要结局
1) Duration of analgesia
时间窗: Intraoperative assessment done at Baseline, After boluses of study drugs, Immediately after ETI, 5min, 15min, 30min, 45m, 1h, 1h15m, 1h30m, 1h45m, 2h, until the pneumoperitoneum is released. | Postoperatively assessed at 1hr, 4hr, 8hr, 12hr, and upto 24 hours
2) VAS score
时间窗: Intraoperative assessment done at Baseline, After boluses of study drugs, Immediately after ETI, 5min, 15min, 30min, 45m, 1h, 1h15m, 1h30m, 1h45m, 2h, until the pneumoperitoneum is released. | Postoperatively assessed at 1hr, 4hr, 8hr, 12hr, and upto 24 hours
次要结局
- 1) Intraoperative Hemodynamic parameters at baseline, after boluses of drugs administration, immediately after intubation, 5min & every 15min until the end of the procedure.(2) Side effects like nausea, vomiting & sore throat.)
研究者
Manchala Jyothi Sai Reddy
Kasturba Medical College, Mangalore