COMPARISON OF NEUTROPHIL-TO-LYMPHOCYTE RATIO AND PLATELET INDICES TO PREDICT THE SEVERITY OF ACUTE APPENDICITIS ON HISTOPATHOLOGY - AN OBSERVATIONAL STUDY
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- 1.Neutrophil-to-lymphocyte ratio
研究概览
简要总结
As different study have suggested that both neutrophil to lymphocyte ratio and platelet indices(mean platelet volume and platelet distribution width) are the inflammatory marker and increase during inflammation. Since the positive predictive value of both these indices is different and different studies have said one to be superior to other, so we will be prospectively comparing the neutrophil-to-lymphocyte ratio (NLR) with the Platelets indices by applying both to patient who presented to accident & emergency department and are diagnosed of acute appendicitis to prove which is the superior marker for predicting severity of appendicitis.
this study is being done to compare neutrophil to lymphocyte ration and platelet indices to predict the severity of acute appendicitis on histopathology.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 80.00 Year(s)（—）
- 性别
- All
入选标准
- •Diagnosed case of Acute appendicitis with Alvarado score >7.
排除标准
- •1.Diagnosed case of appendicular lump, perforation peritonitis.
- •2.Myocardial infarction.
- •3.Uncontrolled diabetes mellitus.
- •4.Autoimmune disorders.
- •5.Patients on immunosuppressive therapy.
- •6.Pregnancy and lactation.
结局指标
主要结局
1.Neutrophil-to-lymphocyte ratio
时间窗: at the time of presentation which is 0 hour and after | 1 week
2.Platelet indices (mean platelet volume and platelets distribution width)
时间窗: at the time of presentation which is 0 hour and after | 1 week
3.Histopathological Finding
时间窗: at the time of presentation which is 0 hour and after | 1 week
次要结局
- 1.Duration of symptoms(1. At the time of presentation)