NEUTROPHIL-TO-LYMPHOCYTE RATIO OR PLATELET INDICES, WHAT IS THE BETTER INDICATOR TO PREDICT THE SEVERITY OF ACUTE APPENDICITIS ON HISTOPATHOLOGY- AN OBSERVATIONAL STUDY
- Conditions
- Other and unspecified acute appendicitis,
- Registration Number
- CTRI/2022/02/040582
- Lead Sponsor
- Department of surgery
- Brief Summary
As different study have suggested that both neutrophil to lymphocyte ratio and platelet indices(mean platelet volume and platelet distribution width) are the inflammatory marker and increase during inflammation. Since the positive predictive value of both these indices is different and different studies have said one to be superior to other, so we will be prospectively comparing the neutrophil-to-lymphocyte ratio (NLR) with the Platelets indices by applying both to patient who presented to accident & emergency department and are diagnosed of acute appendicitis to prove which is the superior marker for predicting severity of appendicitis.
this study is being done to compare neutrophil to lymphocyte ration and platelet indices to predict the severity of acute appendicitis on histopathology.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 20
Diagnosed case of Acute appendicitis with Alvarado score >7.
- 1.Diagnosed case of appendicular lump, perforation peritonitis.
- 2.Myocardial infarction.
- 3.Uncontrolled diabetes mellitus.
- 4.Autoimmune disorders.
- 5.Patients on immunosuppressive therapy.
- 6.Pregnancy and lactation.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.Neutrophil-to-lymphocyte ratio at the time of presentation which is 0 hour and after | 1 week 2.Platelet indices (mean platelet volume and platelets distribution width) at the time of presentation which is 0 hour and after | 1 week 3.Histopathological Finding at the time of presentation which is 0 hour and after | 1 week
- Secondary Outcome Measures
Name Time Method 1.Duration of symptoms 1. At the time of presentation
Trial Locations
- Locations (1)
Department of Surgery and Department of Pathology
🇮🇳Central, DELHI, India
Department of Surgery and Department of Pathology🇮🇳Central, DELHI, IndiaDr Vimlendra Kumar ChaudharyPrincipal investigator08860045056surgery.vimlendrakchaudhary.2020@gmail.com