Quadratus Lumborum Block Using Loss-of-resistance Versus Ultrasound-guided Technique
试验速览
- 阶段
- 不适用
- 入组人数
- 16
- 试验地点
- 1
- 主要终点
- Duration of analgesia
研究概览
简要总结
This study aims to explore the feasibility of using loss-of-resistance technique for Quadratus Lumborum block (QLB). And to compare between the Ultrasound guided QLB type II and the loss-of-resistance technique for QLB as regards the degree and duration of analgesia and side effects.
详细描述
Quadratus lumborum block (QLB) is an abdominal plane block with increasing popularity. QLB is achieved by local anesthetic infiltration at the anterolateral aspect of quadratus lumborum muscle (QLB-I), or at the posterior aspect of the muscle (QLB-II), or transmuscular (QL-TM block). Ultrasound-guided technique is the usual route used for QLB performance. QLB had been considered a modification of transversus abdominis plane (TAP) block[4]. A cadaveric study had showed similar local anesthetic spread in both QL and TAP blocks.
TAP block could be performed by using either the ultrasound or loss-of-resistance technique; whilst, QLB is only performed using the ultrasound and the feasibility of loss-of-resistance technique had not been investigated for this block.
This study aims to explore the feasibility of using loss-of-resistance technique for QLB. And to compare between the Ultrasound guided QLB type II and the loss-of-resistance technique for QLB as regards the degree and duration of analgesia and side effects.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients scheduled for lower abdominal surgery under general anesthesia
排除标准
- •Patient refusal to regional block,
- •Pregnancy
- •Coagulopathy
- •Cognitive impairment
- •Inflammation or infection at the puncture site
- •History of allergic reaction to study medications
研究组 & 干预措施
Loss-of-resistance
Patients in this group will receive Loss-of-resistance Quadratus lumborum block with 30 ml bupivacaine 0.25% in addition to general anesthesia.
干预措施: Loss-of-resistance Quadratus lumborum block (Procedure)
Loss-of-resistance
Patients in this group will receive Loss-of-resistance Quadratus lumborum block with 30 ml bupivacaine 0.25% in addition to general anesthesia.
干预措施: General anesthesia (Procedure)
Ultrasound-guided
Patients in this group will receive Ultrasound-guided Quadratus lumborum block type-II with 30 ml bupivacaine 0.25% in addition to general anesthesia.
干预措施: General anesthesia (Procedure)
Ultrasound-guided
Patients in this group will receive Ultrasound-guided Quadratus lumborum block type-II with 30 ml bupivacaine 0.25% in addition to general anesthesia.
干预措施: Ultrasound-guided Quadratus lumborum block (Procedure)
结局指标
主要结局
Duration of analgesia
时间窗: 24 hours
The time between the end of the surgery and the first analgesia request
次要结局
- visual analogue pain score at rest to assess the pain severity(24 hours)
- Postoperative morphine consumption(24 hours)
- Intraoperative extra-analgesia requirements(3 hours)
- Visual analogue pain score at movement to assess the pain severity(24 hours)
- Systolic blood pressure(24 hours)
- Heart rate(24 hours)
研究者
Ahmed Hasanin
Assistant professor
Cairo University