Antibiotic efficacy when extracting lower third molars
Phase 4
Recruiting
- Conditions
- Third molar extractionOral and Gastrointestinal - Other diseases of the mouth, teeth, oesophagus, digestive system including liver and colon
- Registration Number
- ACTRN12619000149167
- Lead Sponsor
- María del Mar Mariscal Cazalla
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 90
Inclusion Criteria
Volunteer patients of the Master of Oral Surgery and Implantology demanding an extraction of a third lower molar
Exclusion Criteria
- Pregnant or breastfeeding period.
-Patients with some systemic pathology. Only patients ASA I (classification of the American Society of Anesthesiology) will be included in the study.
- Previous medical allergies to any drugs used in this study
- Patients have taken antibiotics one week before the surgery
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Presence of infection in patients who have taken antibiotic and those who have not, for the extraction of a third molar.<br>The presence of infection will be assessed according to diagnostic criteria, which are pus in the extraction area, fever higher than 38 ºC after 48 hours or persistent inflammation 7 days later.<br>[At 7 days after intervention]
- Secondary Outcome Measures
Name Time Method Difference of pain in the extraction area between groups, assessed using a Visual Analogue Scale (VAS)[At baseline, at 1 hour, at 2 hours, at 24 hours, at 2 days, at 3 days and at 7 days after intervention];Difference of inflammation in the extraction area between groups, assessed using a Visual Analogue Scale (VAS) and a Gabka and Matsumara Scale[At baseline, at 1 hour, at 2 hours, at 24 hours, ar 2 days, at 3 days and at 7 days after intervention];Use of rescue analgesics between groups.<br>The rescue analgesic will be paracetamol 1 gr, 1 tablet every 8 hours.<br>The patient will be prescribed Ibuprofen 600 mg, 1 tablet every 8 hours as a routine analgesic after extraction. If the patient needs to take rescue analgesic after extraction, we will mark YES on the data collection sheet.[At 7 days after intervention]