Tissue Eosinophils in Non-Small Cell Lung Cancer (the TEN Study)
Active, not recruiting
- Conditions
- Non-small Cell Lung Cancer
- Registration Number
- NCT05537701
- Lead Sponsor
- Centre Hospitalier Universitaire de Liege
- Brief Summary
The primary objective is to describe eosinophil infiltration in resected (early stage) NSCLC.
Secondary objectives are:
* to investigate the correlation of T-Eos and B-Eos in the aforementioned patient population;
* to investigate the correlation between T-Eos and overall \& disease-free survival;
* to investigate the localization of T-Eos (periphery vs. center of the tumor lesions).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 316
Inclusion Criteria
- Resected, early stage NSCLC between 01-01-2015 and 30-04-2022 with available tumour tissue
Exclusion Criteria
- Inclusion in a clinical study contraindicating enrollment in the present study
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Percentage of tumor associated tissue eosinophilia by immunohistochemistry and computerised quantification October 2022
- Secondary Outcome Measures
Name Time Method to investigate the localization of T-Eos (periphery vs. center of the tumor lesions) December 2022 tissue eosinophil localisation
to investigate the correlation of tissue (T)-Eos and blood (B)-Eos in the aforementioned patient population December 2022 Tissue and blood eosinophil correlation
to investigate the correlation between T-Eos and overall & disease-free survival December 2022 overall and disease-free survival
Trial Locations
- Locations (1)
CHU de Liege
🇧🇪Liège, Belgium