跳至主要内容
临床试验/NCT05537701
NCT05537701进行中(未招募)不适用

Tissue Eosinophils in Non-Small Cell Lung Cancer (the TEN Study)

Centre Hospitalier Universitaire de Liege1 个研究点 分布在 1 个国家目标入组 316 人开始时间: 2022年10月3日最近更新:
适应症

试验速览

阶段
不适用
状态
进行中(未招募)
入组人数
316
试验地点
1
主要终点
Percentage of tumor associated tissue eosinophilia by immunohistochemistry and computerised quantification

研究概览

简要总结

The primary objective is to describe eosinophil infiltration in resected (early stage) NSCLC.

Secondary objectives are:

  • to investigate the correlation of T-Eos and B-Eos in the aforementioned patient population;
  • to investigate the correlation between T-Eos and overall & disease-free survival;
  • to investigate the localization of T-Eos (periphery vs. center of the tumor lesions).

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Resected, early stage NSCLC between 01-01-2015 and 30-04-2022 with available tumour tissue

排除标准

  • Inclusion in a clinical study contraindicating enrollment in the present study

结局指标

主要结局

Percentage of tumor associated tissue eosinophilia by immunohistochemistry and computerised quantification

时间窗: October 2022

次要结局

  • to investigate the localization of T-Eos (periphery vs. center of the tumor lesions)(December 2022)
  • to investigate the correlation of tissue (T)-Eos and blood (B)-Eos in the aforementioned patient population(December 2022)
  • to investigate the correlation between T-Eos and overall & disease-free survival(December 2022)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Anne Sibille

Principal investigator

Centre Hospitalier Universitaire de Liege

研究点 (1)

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