MedPath

NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES

🇺🇸United States
Ownership
-
Employees
-
Market Cap
-
Website

Clinical Trials

2.4k

Active:60
Completed:1872

Trial Phases

6 Phases

Early Phase 1:16
Phase 1:938
Phase 2:524
+3 more phases

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (1888 trials with phase data)• Click on a phase to view related trials

Phase 1
938 (49.7%)
Phase 2
524 (27.8%)
Not Applicable
191 (10.1%)
Phase 3
159 (8.4%)
Phase 4
60 (3.2%)
Early Phase 1
16 (0.8%)

L9LS-R21 Interaction

Not Applicable
Not yet recruiting
Conditions
Malaria
Interventions
Drug: Single dose of 1800 mg L9LS SC (12mL)
Drug: Single dose of 225 mg L9LS SC (1.5mL)
Other: Placebo 12 mL SC
Other: Placebo 1.5 mL SC
First Posted Date
2025-10-06
Last Posted Date
2025-10-06
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
357
Registration Number
NCT07208760
Locations
🇲🇱

Sotuba Malaria Research and Training Center (MRTC), Sotouba, Mali

Randomized Stepped Wedge Study of Emapalumab in APECED Enteritis

Not Applicable
Not yet recruiting
Conditions
Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy Enteritis
Interventions
First Posted Date
2025-10-02
Last Posted Date
2025-10-07
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
10
Registration Number
NCT07202598
Locations
🇺🇸

National Institutes of Health Clinical Center, Bethesda, Maryland, United States

Safety and Immunogenicity Trial of PepGNP-COVID19 Vaccine in Adults

Not Applicable
Not yet recruiting
Conditions
COVID-19
Interventions
Biological: PepGNP-COVID19
Other: Sterile Water for Injection
First Posted Date
2025-09-19
Last Posted Date
2025-10-07
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
60
Registration Number
NCT07183709

First-in-Human Study of VNT-101: Safety, Tolerability, and Pharmacokinetics

Not Applicable
Recruiting
Conditions
Influenza
Interventions
Other: Placebo for VNT-101
First Posted Date
2025-09-11
Last Posted Date
2025-10-03
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
78
Registration Number
NCT07169318
Locations
🇺🇸

Altasciences Inc - Kansas City, Overland Park, Kansas, United States

Improving Physical Ability and Cellular Senescence Elimination in HIV

Not Applicable
Not yet recruiting
Conditions
HIV
Frailty
Prefrail
Aging Problems
Interventions
Other: Placebo - Dasatinib
Other: Placebo - Quercetin
First Posted Date
2025-08-27
Last Posted Date
2025-09-25
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
80
Registration Number
NCT07144293
Locations
🇺🇸

The Ponce de Leon Center CRS (Site ID: 5802), Atlanta, Georgia, United States

🇺🇸

Alabama CRS (Site ID: 31788), Birmingham, Alabama, United States

🇺🇸

University of California, Los Angeles CARE Center CRS (Site ID: 601), Los Angeles, California, United States

and more 24 locations
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News

Single-Dose Benzathine Penicillin G Proves as Effective as Three-Dose Regimen for Early Syphilis Treatment

A randomized clinical trial of 249 participants found that a single injection of benzathine penicillin G achieved 76% serologic response compared to 70% with the three-dose regimen at 6 months.

NIH Awards $8.4 Million to OHSU Scientists to Develop HIV Cure Through Study of Three Cured Patients

Oregon Health & Science University researchers received $8.4 million from the National Institute of Allergy and Infectious Diseases to study three individuals who were cured of HIV through stem cell transplants.

Capricor Therapeutics Initiates First-in-Human Trial of StealthX Exosome-Based Vaccine Platform

Capricor Therapeutics has dosed the first subjects in a Phase 1 clinical trial of its StealthX exosome-based vaccine, marking the first-in-human evaluation of this novel platform.

Soligenix Advances SGX943 as Novel Antibiotic Alternative to Combat Drug-Resistant Bacterial Infections

Soligenix is developing SGX943 (dusquetide), a novel broad-spectrum therapy designed to treat bacterial infections without relying on conventional antibiotics.

Saint Louis University Launches Phase 1 Trial for Investigational West Nile Virus Vaccine

Saint Louis University's Center for Vaccine Development will enroll up to 30 healthy adult volunteers in a Phase 1 clinical trial to evaluate the safety and immune response of an updated investigational West Nile virus vaccine.

HHS and NIH Launch "Generation Gold Standard" Universal Vaccine Platform to Combat Pandemic Threats

The U.S. Department of Health and Human Services and NIH have announced "Generation Gold Standard," a next-generation universal vaccine platform using beta-propiolactone-inactivated whole-virus technology.

Three Pharmaceutical Companies Advance Next-Generation COVID-19 Therapeutics in Clinical Trials

INOVIO Pharmaceuticals reports promising Phase I results for its DMAbs technology, showing 100% of subjects maintained relevant antibody levels with no serious adverse events.

NIH Launches First Clinical Trial of Moderna's mRNA Vaccine Against Deadly Nipah Virus

The National Institutes of Health has initiated the first human trial of Moderna's mRNA-1215 vaccine targeting Nipah virus, a deadly pathogen with a 40-70% fatality rate.

HIV Cure Trials at CROI 2025 Show Promise for Broader Patient Applications

At the 2025 Conference on Retroviruses and Opportunistic Infections (CROI), researchers presented promising results from multiple HIV cure trials, suggesting potential for wider therapeutic applications.

NIH Launches First Human Trial of LASSARAB Vaccine for Deadly Lassa Fever

The NIH has initiated a Phase 1 clinical trial of LASSARAB, a novel vaccine candidate for Lassa fever, a viral hemorrhagic disease that can be fatal and causes permanent hearing loss in up to one-third of patients.

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