Comparison of Viscoelastic Properties of Respiratory Muscles and Peripheral Muscles in Chronic Obstructive Pulmonary Disease Patients With Healthy Subjects
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Respiratory functions (PEF)
研究概览
简要总结
The aim of this study was to compare the viscoelastic properties of auxiliary respiratory muscles and peripheral muscles of chronic obstructive pulmonary disease patients with healthy subjects. Myotonometry was used to evaluate the viscoelastic properties of the muscles. The viscoelastic properties of the sternoclaidus mastoid, pectoralis major, upper trapezius, deltoid, biceps brachii, rectus femoris, gastrocinemius, and tibialis anterior muscles were evaluated.
详细描述
muscle viscoelastic properties; muscle tone, stiffness and elasticity. These features may vary due to muscle overuse, lack of relaxation and recovery. The aim is to investigate these differences in COPD patients and healthy individuals.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 40 Years 至 —（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •male gender,
- •body mass index (BMI) between 18.5-29.9 kg/m2,
- •stable COPD patients
排除标准
- •being in the acute exacerbation period for COPD patients,
- •having undergone any neurological, orthopaedic or thoracic surgery,
- •presence of malignancy in any organ,
- •presence of comorbidities affecting muscle atrophy (myasthenia gravis, muscular dystrophy, etc.).
结局指标
主要结局
Respiratory functions (PEF)
时间窗: 1 Day
Peak expiratory flow (PEF) were measured was evaluated with spirometry. It will be recorded as liters and expected percentage
The Medical Research Council Scale
时间窗: 1 Day
Patients simply indicate on the scale the level of activity that causes dyspnoea in them according to the activities between 0-4.
The COPD Assessment Test
时间窗: 1 Day
This statement describes a scale consisting of eight items, each with response values ranging from 0 to 5. The total score is calculated by summing the responses to all the items, resulting in a range from 0 to 40. A higher total score indicates a greater negative impact of the disease on the individual's quality of life and daily activities.
Viscoelastic properties of muscles
时间窗: 1 Day
The viscoelastic properties of the muscles (muscle tone (Hz), and elasticity (Relative), stiffness (N/m)) were measured using a hand-held myotonometer.
Respiratory functions (FEV1)
时间窗: 1 Day
In pulmonary function test was evaluated with spirometry. forced expiratory volume in the first second (FEV1);will be recorded as liters and expected percentage
Respiratory functions (FVC)
时间窗: 1 Day
In pulmonary function test was evaluated with spirometry. forced expiratory volume in the first second (FEV1);will be recorded as liters and expected percentage
Respiratory functions (FEV1/FVC)
时间窗: 1 Day
ratio of forced expiratory volume in the first second to vital capacity (FEV1/FVC) was evaluated with spirometry.
次要结局
未报告次要终点
研究者
Çağtay Maden
Assistant professor
Gaziantep Islam Science and Technology University